Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.34 |
| ▸ | NAT1 | P18440 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12727727 | 0.87 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| SCHEMBL87403 | 0.82 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| SCHEMBL79111 | 0.82 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| SCHEMBL91400 | 0.81 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| SCHEMBL12727762 | 0.80 | CYP1A2 (0.37) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| SCHEMBL14094862 | 0.79 | TUBB4A (0.34) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| SCHEMBL12727724 | 0.79 | TUBB4A (0.37) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| SCHEMBL91374 | 0.76 | MEN1 (0.36) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| SCHEMBL12727719 | 0.74 | POLB (0.35) | CYP1A2CYP2C9CYP2C19RAF1CDK1 | |
| SCHEMBL12727822 | 0.74 | TUBB4A (0.32) | CYP1A2CYP2C9CYP2C19RAF1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221122-A1 | ANALOGS OF DEHYDROPHENYLAHISTINS AND THEIR THEAPEUTIC USE | BEYONDSPRING PHARMACEUTICALS, INC. | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221122-A1 | ANALOGS OF DEHYDROPHENYLAHISTINS AND THEIR THEAPEUTIC USE | HPGDS, DHPS, HCCS | CYP1A2 1594/4885CYP2C9 3869/4885CYP2C19 2655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.