Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14768457 | 1.00 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL12101256 | 1.00 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL23583784 | 0.90 | LMNA (0.41) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL12292855 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL5272544 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL19240032 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL15761692 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPK1CYP3A4TDP1 | |
| SCHEMBL21470237 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPK1CYP3A4TDP1 | |
| SCHEMBL2398261 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL12101253 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7407648-B2 | Merocyanine derivatives for cosmetic use | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-08-05 | — | — | US | disclosed |
| US-7407648-B2 | Merocyanine derivatives for cosmetic use | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-08-05 | — | — | US | disclosed |