Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2398261 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL2398264 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL18698664 | 1.00 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL12101263 | 0.94 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL14768429 | 0.94 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL14095062 | 0.94 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL12292855 | 0.89 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL5272544 | 0.89 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL12668069 | 0.83 | TSHR (0.48) | ALDH1A1LMNAMAPK1TSHRCYP3A4 | |
| SCHEMBL12667157 | 0.82 | TSHR (0.47) | ALDH1A1LMNAMAPK1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11045409-B2 | Composition comprising a water-insoluble solid organic UV-screening agent and a compound capable of establishing hydrogen bonds | L'OREAL (FR) | 2021-06-29 | — | — | US | disclosed |
| EP-2683351-B1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | OREAL (FR) | 2019-10-16 | — | — | EP | disclosed |
| EP-3019143-B1 | COMPOSITION COMPRISING A WATER-INSOLUBLE SOLID ORGANIC UV-SCREENING AGENT AND A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS | OREAL (FR) | 2019-03-13 | — | — | EP | disclosed |
| US-9656103-B2 | Light protecting-effective cosmetic or dermatological preparations | BASF SE (DE) | 2017-05-23 | — | — | US | disclosed |
| US-9656103-B2 | Light protecting-effective cosmetic or dermatological preparations | BASF SE (DE) | 2017-05-23 | — | — | US | disclosed |
| US-20160151267-A1 | COMPOSITION COMPRISING A WATER-INSOLUBLE SOLID ORGANIC UV-SCREENING AGENT AND A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS | L'OREAL (FR) | 2016-06-02 | — | — | US | disclosed |
| US-20160151267-A1 | COMPOSITION COMPRISING A WATER-INSOLUBLE SOLID ORGANIC UV-SCREENING AGENT AND A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS | L'OREAL (FR) | 2016-06-02 | — | — | US | disclosed |
| US-20160067160-A1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | OREAL (FR) | 2016-03-10 | — | — | US | disclosed |
| US-20160067160-A1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | OREAL (FR) | 2016-03-10 | — | — | US | disclosed |
| US-20150284330-A1 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | OREAL (FR) | 2015-10-08 | — | — | US | disclosed |
| US-20130064871-A1 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | L'OREAL (FR) | 2013-03-14 | — | — | US | disclosed |
| WO-2012119860-A1 | COSMETIC COMPOSITION CONTAINING A DIBENZOYLMETHANE DERIVATIVE AND A MONOESTER-MONOAMIDE COMPOUND OF METHYLSUCCINIC ACID; PROCESS FOR PHOTOSTABILIZING A DIBENZOYLMETHANE DERIVATIVE | L'OREAL (FR) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012119861-A2 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | L'OREAL (FR) | 2012-09-13 | — | — | WO | disclosed |
| EP-1549283-B1 | Cosmetic preparation comprising merocyanine derivatives | BASF SE (DE) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011113719-A2 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | L'OREAL (FR) | 2011-09-22 | — | — | WO | disclosed |
| EP-1768644-B1 | LIGHT PROTECTING-EFFECTIVE COSMETIC OR DERMATOLOGICAL PREPARATIONS | CIBA HOLDING INC (CH) | 2009-02-18 | — | — | EP | disclosed |
| US-7407648-B2 | Merocyanine derivatives for cosmetic use | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-08-05 | — | — | US | disclosed |
| US-7407648-B2 | Merocyanine derivatives for cosmetic use | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-08-05 | — | — | US | disclosed |
| US-20080075746-A1 | Dispersing insoluble or sparingly soluble micronized substance in oil or water phase; adding soluble ultraviolet radiation filter that is not a cosmetic UV absorber; remarkable increase in (SPF) sun protection factor; sunscreen agents | CIBA SPECIALTY CHEMICALS CORPORATION | 2008-03-27 | — | — | US | disclosed |
| US-20080075746-A1 | Dispersing insoluble or sparingly soluble micronized substance in oil or water phase; adding soluble ultraviolet radiation filter that is not a cosmetic UV absorber; remarkable increase in (SPF) sun protection factor; sunscreen agents | CIBA SPECIALTY CHEMICALS CORPORATION | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130064871-A1 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | DDT, PCCA, DDC | ALDH1A1 1102/4885LMNA 911/4885MAPK1 3289/4885 |
| US-20160151267-A1 | COMPOSITION COMPRISING A WATER-INSOLUBLE SOLID ORGANIC UV-SCREENING AGENT AND A COMPOUND CAPABLE OF ESTABLISHING HYDROGEN BONDS | F2, F12, C1S | ALDH1A1 1323/4885LMNA 1274/4885MAPK1 1719/4885 |
| US-11045409-B2 | Composition comprising a water-insoluble solid organic UV-screening agent and a compound capable of establishing hydrogen bonds | F2, F12, C1S | ALDH1A1 1323/4885LMNA 1274/4885MAPK1 1719/4885 |
| US-20080075746-A1 | Dispersing insoluble or sparingly soluble micronized substance in oil or water phase; adding soluble ultraviolet radiation filter that is not a cosmetic UV absorber; remarkable increase in (SPF) sun protection factor; sunscreen agents | CUTA, MITF, MIF | ALDH1A1 1973/4885LMNA 1779/4885MAPK1 3452/4885 |
| US-20160067160-A1 | USE OF A 2-METHYLSUCCINIC ACID DIESTER DERIVATIVE AS SOLVENT IN COSMETIC COMPOSITIONS; COSMETIC COMPOSITIONS CONTAINING THE SAME | DIMT1, FADS2, SCD | ALDH1A1 390/4885LMNA 2770/4885MAPK1 2124/4885 |
| US-20150284330-A1 | COMPOSITION COMPRISING A DIBENZOYLMETHANE SCREENING AGENT AND A MEROCYANINE DICYANO OR CYANOACETATE DERIVATIVE; METHOD FOR THE PHOTOSTABILIZATION OF THE DIBENZOYLMETHANE SCREENING AGENT | DDT, PCCA, DDC | ALDH1A1 1102/4885LMNA 911/4885MAPK1 3289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.