Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 5/20 | 0.44 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 4/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | FABP6 | P51161 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14095865 | 0.81 | TGM2 (0.54) | KMT2AMEN1EBPDHCR7TPSAB1 | |
| SCHEMBL14045064 | 0.80 | DPP4 (0.43) | KMT2AMEN1HTTNAMPTMAPT | |
| SCHEMBL14095882 | 0.78 | ALDH1A1 (0.55) | KMT2AMEN1PKMSMN1; SMN2NAMPT | |
| SCHEMBL14095878 | 0.78 | EBP (0.56) | KMT2AMEN1EBPDHCR7PKM | |
| SCHEMBL3296336 | 0.78 | MAPT (0.44) | KMT2AMEN1NAMPTMAPT | |
| SCHEMBL14095885 | 0.77 | PKM (0.51) | KMT2AMEN1PKMMAPT | |
| SCHEMBL14095881 | 0.77 | KMT2A (0.55) | KMT2AMEN1SMYD3EBPDHCR7 | |
| SCHEMBL14095883 | 0.74 | ADRB3 (0.46) | KMT2AMEN1EBPDHCR7PKM | |
| SCHEMBL14095884 | 0.73 | MEN1 (0.47) | KMT2AMEN1SMYD3EBPDHCR7 | |
| SCHEMBL17484487 | 0.71 | KCNJ1 (0.42) | KMT2AMEN1PKMHTTKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099073-A1 | N, N' -2, 4-DIANILINOPYRIMIDINES PREPARATION AND USE THEREOF AS IKK INHIBITORS PREPARATION AND TEH PHARMACUETICAL COMPOSITIONS THEREOF | SANOFI-AVENTIS (FR) | 2008-08-21 | — | — | WO | disclosed |