Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 10/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.57 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.57 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14095980 | 0.88 | ALDH1A1 (0.64) | ALDH1A1MAPTCYP1A2GAACYP2C9 | |
| SCHEMBL14095965 | 0.88 | ALDH1A1 (0.63) | ALDH1A1MAPTCYP1A2GAACYP2C9 | |
| SCHEMBL4366220 | 0.87 | MAPT (0.63) | ALDH1A1MAPTCYP1A2GAACYP2C9 | |
| SCHEMBL14095985 | 0.87 | KMT2A (0.64) | ALDH1A1MAPTCYP1A2GAACYP2C9 | |
| SCHEMBL14137019 | 0.87 | CYP1A2 (0.65) | ALDH1A1MAPTCYP1A2GAACYP2C9 | |
| SCHEMBL13956729 | 0.84 | MAPT (0.60) | ALDH1A1MAPTCYP1A2GAACYP2C9 | |
| SCHEMBL4361509 | 0.83 | HPGD (0.75) | ALDH1A1MAPTCYP1A2GAACYP2C9 | |
| SCHEMBL14096555 | 0.83 | SIRT1 (0.62) | ALDH1A1MAPTGAASMN1; SMN2SIRT1 | |
| SCHEMBL12251325 | 0.83 | ESR1 (0.68) | ALDH1A1MAPTCYP1A2GAACYP2C9 | |
| SCHEMBL12067341 | 0.83 | SIRT1 (0.71) | ALDH1A1MAPTSMN1; SMN2HPGDSIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | RNASE1, SARS1, EIF2AK2 | ALDH1A1 2930/4885MAPT 4038/4885CYP1A2 1316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.