Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | TP53 | P04637 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 3/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | DUSP1 | P28562 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14096560 | 0.83 | MAPT (0.83) | NPC1RAB9AMAPTTP53ALDH1A1 | |
| SCHEMBL31451702 | 0.75 | MAPT (0.69) | NPC1RAB9AMAPTTP53ALDH1A1 | |
| SCHEMBL4361940 | 0.75 | SMN1; SMN2 (1.00) | NPC1RAB9AMAPTTP53ALDH1A1 | |
| SCHEMBL14096547 | 0.75 | ALDH1A1 (0.79) | NPC1RAB9AMAPTTP53ALDH1A1 | |
| SCHEMBL31451268 | 0.74 | MAPT (0.67) | NPC1RAB9AMAPTTP53ALDH1A1 | |
| SCHEMBL31451507 | 0.74 | MAPT (0.64) | NPC1RAB9AMAPTTP53ALDH1A1 | |
| SCHEMBL14096588 | 0.73 | ALDH1A1 (0.61) | NPC1RAB9AMAPTTP53ALDH1A1 | |
| SCHEMBL31451443 | 0.73 | TP53 (0.66) | NPC1RAB9AMAPTTP53ALDH1A1 | |
| SCHEMBL31451710 | 0.73 | MAPT (0.66) | MAPTTP53ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL31451706 | 0.73 | MAPT (0.71) | NPC1RAB9AMAPTTP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | RNASE1, SARS1, EIF2AK2 | NPC1 886/4885RAB9A 3144/4885MAPT 4038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.