SCHEMBL140975

SCHEMBL140975

O=C1C=CC(=O)N1Cc1cccc(CN2C(=O)C=CC2=O)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 9/20 0.72
GSK3A P49840 5/20 0.72
GSK3B P49841 5/20 0.72
FAAH O00519 4/20 0.67
PTGS1 P23219 2/20 0.50
PTGS2 P35354 2/20 0.50
CMA1 P23946 2/20 0.47
F2 P00734 1/20 0.46
PLG P00747 1/20 0.46
ELANE P08246 1/20 0.46
CTSG P08311 1/20 0.46
CTRC Q99895 1/20 0.46
KMT2A Q03164 1/20 0.42
CASP3 P42574 1/20 0.41
GMNN O75496 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
THPO P40225 1/20 0.41
BLM P54132 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17532637 0.89 MGLL (0.58) MGLLGSK3AGSK3BFAAHPTGS1
SCHEMBL20804240 0.86 MGLL (0.60) MGLLGSK3AGSK3BFAAHPTGS1
SCHEMBL7224603 0.86 MGLL (0.60) MGLLGSK3AGSK3BFAAHPTGS1
SCHEMBL7224723 0.86 MGLL (0.60) MGLLGSK3AGSK3BFAAHPTGS1
SCHEMBL28411433 0.86 MGLL (0.60) MGLLGSK3AGSK3BFAAHKMT2A
SCHEMBL15660656 0.86 MGLL (0.60) MGLLGSK3AGSK3BFAAHPTGS1
SCHEMBL6388547 0.86 MGLL (0.60) MGLLGSK3AGSK3BFAAHPTGS1
SCHEMBL7101837 0.85 MGLL (0.67) MGLLGSK3AGSK3BFAAHALDH1A1
SCHEMBL24119837 0.84 MGLL (0.53) MGLLGSK3AGSK3BFAAHPTGS1
SCHEMBL207740 0.84 MGLL (1.00) MGLLGSK3AGSK3BFAAHPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 516 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12460136-B2 Flame-retardant composition CHANG CHUN PLASTICS CO., LTD. (TW) 2025-11-04 US claimed
CN-119431678-A Flame retardant composition 长春人造树脂厂股份有限公司 2025-02-14 CN claimed
US-20250051645-A1 FLAME-RETARDANT COMPOSITION CHANG CHUN PLASTICS CO., LTD. (TW) 2025-02-13 US claimed
US-20240351981-A1 NOVEL BISMALEIMIDE COMPOUNDS HAVING IMPROVED SOLUBILITY AND THEIR USE IN CURABLE COMPOSITIONS EVONIK OPERATIONS GMBH (DE) 2024-10-24 US claimed
US-20240327681-A1 BONDING SYSTEM DDP SPECIALTY ELECTRONIC MATERIALS US LLC (US) 2024-10-03 US claimed
EP-4380922-A1 NOVEL BISMALEIMIDE COMPOUNDS HAVING IMPROVED SOLUBILITY AND THEIR USE IN CURABLE COMPOSITIONS Evonik Operations GmbH (DE) 2024-06-12 EP claimed
US-20240084135-A1 RESIN COMPOSITION, AND PREPREG, METAL-CLAD LAMINATE AND PRINTED CIRCUIT BOARD PREPARED USING THE SAME TAIWAN UNION TECHNOLOGY CORPORATION (TW) 2024-03-14 US claimed
CN-117624837-A Resin composition, and prepreg, metal foil laminate and printed wiring board produced using the same 台燿科技股份有限公司 2024-03-01 CN claimed
CN-111690247-B Resin composition and use thereof 台燿科技股份有限公司 2024-01-02 CN claimed
WO-2023011938-A1 NOVEL BISMALEIMIDE COMPOUNDS HAVING IMPROVED SOLUBILITY AND THEIR USE IN CURABLE COMPOSITIONS EVONIK OPERATIONS GMBH (DE) 2023-02-09 WO claimed
EP-0165812-B1 THERMOSETTING IMIDE RESIN COMPOSITIONS The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1988-11-09 EP claimed
US-4738900-A HEAT RESISTANT DIELECTRIC LAYER OF A POLYMER OF AN AROMATIC DIMALEIMIDE AND AN AROMATIC DICYANAMIDE HITACHI, LTD. (JP) 1988-04-19 US claimed
US-4737568-A Curable resin from bis-imide amino acid hydrazide and alkenyl phenol or ether THE BOOTS COMPANY PLC (GB) 1988-04-12 US claimed
EP-0212808-A2 Curable resins Technochemie GmbH - Verfahrenstechnik (DE) 1987-03-04 EP claimed
EP-0131027-B1 CURABLE THERMOSETTING PREPOLYMERISED IMIDE RESIN COMPOSITIONS The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and (GB) 1986-12-17 EP claimed
EP-0202498-A2 Use of a thermo-setting, polymerizable composition and wiring board HITACHI, LTD. (JP) 1986-11-26 EP claimed
EP-0141612-A2 Curable Bisimide Resin Mixtures Technochemie GmbH - Verfahrenstechnik (DE) 1985-05-15 EP claimed
US-4390596-A POLYAMINE, BIS-MALEIMIDE, FREE RADICAL CATALYST, FILLER RHONE-POULENC INDUSTRIES (FR) 1983-06-28 US claimed
US-4238591-A BIS-MALEIMIDE, SILANEDIOL OR SILOXANE RHONE-POULENC INDUSTRIES (FR) 1980-12-09 US claimed
US-4035345-A Thermosetting bis-imide compositions RHONE-POULENC S.A. (FR) 1977-07-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240351981-A1 NOVEL BISMALEIMIDE COMPOUNDS HAVING IMPROVED SOLUBILITY AND THEIR USE IN CURABLE COMPOSITIONS PBRM1, SMCHD1, SMARCE1 MGLL 3949/4885GSK3A 3136/4885GSK3B 3259/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.