SCHEMBL15660656

SCHEMBL15660656

O=C1C=CC(=O)N1Cc1cccc(I)c1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 6/20 0.60
GSK3A P49840 4/20 0.60
GSK3B P49841 4/20 0.60
FAAH O00519 4/20 0.55
PTGS1 P23219 2/20 0.43
PTGS2 P35354 2/20 0.43
IDO1 P14902 2/20 0.43
HTR2C P28335 1/20 0.42
CMA1 P23946 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL140975 0.86 MGLL (0.72) MGLLGSK3AGSK3BFAAHPTGS1
SCHEMBL17114059 0.79 KMT2A (0.42) FAAHIDO1HTR2CCMA1
SCHEMBL12204465 0.79 KMT2A (0.60)
SCHEMBL6388547 0.78 MGLL (0.60) MGLLGSK3AGSK3BFAAHPTGS1
SCHEMBL28411433 0.78 MGLL (0.60) MGLLGSK3AGSK3BFAAHIDO1
SCHEMBL20804240 0.78 MGLL (0.60) MGLLGSK3AGSK3BFAAHPTGS1
SCHEMBL7224603 0.78 MGLL (0.60) MGLLGSK3AGSK3BFAAHPTGS1
SCHEMBL7224723 0.78 MGLL (0.60) MGLLGSK3AGSK3BFAAHPTGS1
SCHEMBL30799219 0.77 MEN1 (0.51) FAAHIDO1HTR2C
SCHEMBL27385975 0.77 MEN1 (0.51) FAAHIDO1HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3089962-B1 RADIOIODINATED COMPOUNDS NUTECH VENTURES (US) 2019-03-13 EP disclosed
EP-3089962-B1 RADIOIODINATED COMPOUNDS NUTECH VENTURES (US) 2019-03-13 EP disclosed
US-10053423-B2 Radioiodinated compounds NUTECH VENTURES (US) 2018-08-21 US disclosed
CN-106536490-A Radioiodinated compounds 纽泰克温图斯公司 2017-03-22 CN disclosed
US-20160326109-A1 RADIOIODINATED COMPOUNDS BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2016-11-10 US disclosed
US-20160326109-A1 RADIOIODINATED COMPOUNDS BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2016-11-10 US disclosed
US-20160326109-A1 RADIOIODINATED COMPOUNDS BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2016-11-10 US disclosed
EP-3089962-A2 RADIOIODINATED COMPOUNDS Nutech Ventures (US) 2016-11-09 EP disclosed
WO-2015147950-A2 RADIOIODINATED COMPOUNDS NUTECH VENTURES (US) 2015-10-01 WO disclosed
WO-2015147950-A2 RADIOIODINATED COMPOUNDS NUTECH VENTURES (US) 2015-10-01 WO disclosed
EP-2912011-A1 PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS Ground Fluor Pharmaceuticals Inc. (US) 2015-09-02 EP disclosed
WO-2014066772-A1 PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS Ground Fluor Pharmaceuticals, Inc. (US) 2014-05-01 WO disclosed
US-20140121371-A1 PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS Ground Fluor Pharmaceuticals, Inc. (US) 2014-05-01 US disclosed
US-20140121371-A1 PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS Ground Fluor Pharmaceuticals, Inc. (US) 2014-05-01 US disclosed
US-20140121371-A1 PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS Ground Fluor Pharmaceuticals, Inc. (US) 2014-05-01 US disclosed
WO-2014066772-A1 PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS Ground Fluor Pharmaceuticals, Inc. (US) 2014-05-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160326109-A1 RADIOIODINATED COMPOUNDS SLC7A5, DDC, PAICS MGLL 3377/4885GSK3A 3973/4885GSK3B 3819/4885
US-20140121371-A1 PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS ABL1, ARSA, AADAC MGLL 969/4885GSK3A 4116/4885GSK3B 3994/4885
US-10053423-B2 Radioiodinated compounds SLC7A5, DDC, PAICS MGLL 3377/4885GSK3A 3973/4885GSK3B 3819/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.