SCHEMBL7224723

SCHEMBL7224723

Cc1cccc(CN2C(=O)C=CC2=O)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 5/20 0.60
GSK3A P49840 2/20 0.60
GSK3B P49841 2/20 0.60
FAAH O00519 2/20 0.55
KMT2A Q03164 4/20 0.53
POLB P06746 3/20 0.53
MEN1 O00255 3/20 0.53
MAPT P10636 3/20 0.50
TP53 P04637 1/20 0.50
HSP90AA1 P07900 1/20 0.50
LMNA P02545 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
USP2 O75604 1/20 0.49
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.49
ATM Q13315 1/20 0.49
PTGS1 P23219 1/20 0.49
PTGS2 P35354 1/20 0.49
ALDH1A1 P00352 3/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL140975 0.86 MGLL (0.72) MGLLGSK3AGSK3BFAAHKMT2A
SCHEMBL20804319 0.80 ALDH1A1 (0.58) KMT2APOLBMEN1MAPTTP53
SCHEMBL20437111 0.79 KMT2A (0.51) KMT2APOLBMEN1MAPTTP53
SCHEMBL29819860 0.79 KMT2A (0.60) KMT2APOLBMEN1MAPTNPSR1
SCHEMBL10922984 0.79 KMT2A (0.60) KMT2APOLBMEN1MAPTNPSR1
SCHEMBL7224603 0.78 MGLL (0.60) MGLLGSK3AGSK3BFAAHKMT2A
SCHEMBL20804240 0.78 MGLL (0.60) MGLLGSK3AGSK3BFAAHMAPT
SCHEMBL28411433 0.78 MGLL (0.60) MGLLGSK3AGSK3BFAAHKMT2A
SCHEMBL6388547 0.78 MGLL (0.60) MGLLGSK3AGSK3BFAAHPTGS1
SCHEMBL15660656 0.78 MGLL (0.60) MGLLGSK3AGSK3BFAAHPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113136239-B Utilization method of ethylene cracking tar and application of compound containing carbon-carbon double bond 清华大学 2022-05-13 CN disclosed
CN-113563152-A Method for treating C five fraction and use of olefinic bond-containing compound 清华大学 2021-10-29 CN disclosed
CN-113136239-A Utilization method of ethylene cracking tar and application of compound containing carbon-carbon double bond 清华大学 2021-07-20 CN disclosed
CN-113122315-A Method for treating ethylene tar and use of carbonyl compound containing olefinic bond 清华大学 2021-07-16 CN disclosed
CN-113024724-A Method for continuous polymerization of cracked fractions 清华大学 2021-06-25 CN disclosed
CN-112852482-A Method for treating cracked fractions and use of compounds containing olefinic bonds 清华大学 2021-05-28 CN disclosed
EP-3089962-B1 RADIOIODINATED COMPOUNDS NUTECH VENTURES (US) 2019-03-13 EP disclosed
US-20160326109-A1 RADIOIODINATED COMPOUNDS BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2016-11-10 US disclosed
US-20160326109-A1 RADIOIODINATED COMPOUNDS BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2016-11-10 US disclosed
WO-2015147950-A2 RADIOIODINATED COMPOUNDS NUTECH VENTURES (US) 2015-10-01 WO disclosed
US-20140121371-A1 PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS Ground Fluor Pharmaceuticals, Inc. (US) 2014-05-01 US disclosed
US-6627364-B2 Contains (A) a colorant, (B) a binder resin and (C) a solvent having a boiling point of 245 degrees C. or more at normal pressure. SEIKO EPSON CORPORATION (JP) 2003-09-30 US disclosed
US-20020128351-A1 Ink jet color filter resin composition, color filter and color filter production process SEIKO EPSON CORPORATION (JP) 2002-09-12 US disclosed
EP-1048700-A1 Ink jet color filter resin composition, color filter production process SEIKO EPSON CORPORATION (JP) 2000-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160326109-A1 RADIOIODINATED COMPOUNDS SLC7A5, DDC, PAICS MGLL 3377/4885GSK3A 3973/4885GSK3B 3819/4885
US-20140121371-A1 PROCESSES AND REAGENTS FOR MAKING DIARYLIODONIUM SALTS ABL1, ARSA, AADAC MGLL 969/4885GSK3A 4116/4885GSK3B 3994/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.