Adipic Acid

Adipic Acid

SCHEMBL1409802

CCCCOCCOCCOCc1ccccc1.O=C(O)CCCCC(=O)O

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC18A2SLC6A2SLC6A3

The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 known ✓ Q01959 1/20 0.46
ALDH1A1 P00352 3/20 0.51
MAPK1 P28482 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
CYP3A4 P08684 1/20 0.51
TSHR P16473 1/20 0.51
PLA2G4B P0C869 2/20 0.49
MAPT P10636 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
HPGD P15428 1/20 0.47
HDAC3 O15379 1/20 0.46
ADRA1A P35348 1/20 0.46
HDAC4 P56524 1/20 0.46
HDAC1 Q13547 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC2 Q92769 1/20 0.46
HDAC10 Q969S8 1/20 0.46
HDAC11 Q96DB2 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL2045444 0.95 ALDH1A1 (0.52) ALDH1A1MAPK1TDP1L3MBTL1CYP3A4
SCHEMBL25801992 0.91 MAPT (0.53) MAPK1L3MBTL1TSHRMAPTRXFP1
Adipic Acid SCHEMBL2784118 0.89 MAPT (0.49) ALDH1A1MAPK1TDP1L3MBTL1CYP3A4
SCHEMBL29132549 0.89 MAPT (0.56) MAPK1TDP1L3MBTL1TSHRMAPT
SCHEMBL31482293 0.89 MAPT (0.56) MAPK1TDP1L3MBTL1TSHRMAPT
SCHEMBL31482287 0.89 MAPT (0.56) MAPK1TDP1L3MBTL1TSHRMAPT
SCHEMBL22367410 0.89 SMN1; SMN2 (0.53) ALDH1A1MAPK1TSHRMAPTRXFP1
SCHEMBL28435352 0.89 PLA2G4B (0.48) ALDH1A1MAPK1TDP1L3MBTL1CYP3A4
SCHEMBL712393 0.87 MAPT (0.56) MAPK1TDP1L3MBTL1TSHRMAPT
SCHEMBL3969873 0.87 L3MBTL1 (0.54) ALDH1A1MAPK1TDP1L3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2202267-B1 Plasticizer for biodegradable aliphatic polyester resins, and biodegradable resin composition DAIHACHI CHEM IND (JP) 2011-12-07 EP claimed
EP-2202267-A1 Plasticizer for biodegradable aliphatic polyester resins, and biodegradable resin composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2010-06-30 EP claimed
US-7166654-B2 Ester compound, plasticizer for biodegradable aliphatic polyester resin, and biodegradable resin composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-01-23 US claimed
WO-2024147358-A1 PROCESSING AID, MASTER BATCH, THERMOPLASTIC RESIN COMPOSITION, AND FILM ダイキン工業株式会社 2024-07-11 WO disclosed
WO-2024084885-A1 RESIN COMPOSITION, METHOD FOR PRODUCING RESIN PRODUCT, AND FLAME RETARDANT MASTERBATCH 三菱ケミカル株式会社 2024-04-25 WO disclosed
WO-2024024667-A1 RESIN COMPOSITION AND MOLDING METHOD USING RESIN COMPOSITION 三菱ケミカル株式会社 2024-02-01 WO disclosed
WO-2023171565-A1 RESIN COMPOSITION 三菱ケミカル株式会社 2023-09-14 WO disclosed
US-20230159734-A1 Resin Composition and Molded Body MITSUBISHI CHEMICAL CORPORATION (JP) 2023-05-25 US disclosed
EP-4159804-A1 RESIN COMPOSITION AND MOLDED BODY Mitsubishi Chemical Corporation (JP) 2023-04-05 EP disclosed
WO-2022225024-A1 EMULSION RESIN COMPOSITION AND COATING AGENT 三菱ケミカル株式会社 2022-10-27 WO disclosed
EP-3985057-A1 CELLULOSE RESIN COMPOSITION, MOLDED BODY AND PRODUCT USING SAME NEC Corporation (JP) 2022-04-20 EP disclosed
US-20090316084-A1 Method of Producing Polarizing Plate, Polarizing Plate, and Liquid Crystal Display KONICA MINOLTA OPTO, INC. (JP) 2009-12-24 US disclosed
US-20090286098-A1 Optical Film, Method of Producing the Same and Image Displaying Apparatus Employing the Optical Film KONICA MINOLTA OPTO, INC. (JP) 2009-11-19 US disclosed
EP-2053091-A1 RESIN COMPOSITION, METHOD FOR PRODUCING THE SAME AND MOLDED ARTICLE TEIJIN LIMITED (JP) 2009-04-29 EP disclosed
US-20090030160-A1 Polylactic Acid Complex and Production Method Thereof SUMITOMO ELECTRIC FINE POLYMER INC. (JP) 2009-01-29 US disclosed
US-20080262151-A1 Resin Composition and Molded Article Comprising the Same TORAY INDUSTRIES, INC. (JP) 2008-10-23 US disclosed
US-20080036119-A1 Molding material, molded part, and method for manufacturing them SUMITOMO ELECTRIC FINE POLYMER, INC. 2008-02-14 US disclosed
EP-1792941-A1 RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME TORAY INDUSTRIES, INC. (JP) 2007-06-06 EP disclosed
US-7166654-B2 Ester compound, plasticizer for biodegradable aliphatic polyester resin, and biodegradable resin composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2007-01-23 US disclosed
US-20050228092-A1 Ester compound, plasticizer for bioegradable aliphatic polyester resin, and biodegradable resin composition DAIHACHI CHEMICAL INDUSTRY CO., LTD. (JP) 2005-10-13 US disclosed