SCHEMBL14099199

SCHEMBL14099199

Cc1ccc(/C=C/c2ccc(N(c3ccc(C)cc3)c3cccc4c(N(c5ccc(C)cc5)c5ccc(/C=C/c6ccc(C)cc6)cc5)cccc34)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 7/20 0.43
RELA Q04206 2/20 0.40
APP P05067 2/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
ALOX5 P09917 1/20 0.38
PTGS1 P23219 1/20 0.38
PTGS2 P35354 1/20 0.38
MAT2A P31153 1/20 0.38
KCNH2 Q12809 1/20 0.38
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37
MEN1 O00255 2/20 0.37
APOBEC3A P31941 2/20 0.37
KMT2A Q03164 2/20 0.37
APOBEC3G Q9HC16 2/20 0.37
KDM4E B2RXH2 1/20 0.37
CASP3 P42574 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2153287 0.93 RELA (0.44) NFE2L2RELAAPPTRPM8ALOX5
SCHEMBL14537271 0.93 RELA (0.44) NFE2L2RELAAPPTRPM8ALOX5
SCHEMBL14537277 0.93 RELA (0.44) NFE2L2RELAAPPTRPM8ALOX5
SCHEMBL14099255 0.91 APP (0.43) NFE2L2RELAAPPTRPM8ALOX5
SCHEMBL14537276 0.90 TRPM8 (0.46) NFE2L2RELAAPPTRPM8PTGS2
SCHEMBL14537301 0.88 RELA (0.41) NFE2L2RELAAPPTRPM8ALOX5
SCHEMBL14526499 0.88 TRPM8 (0.42) NFE2L2RELAAPPTRPM8PTGS2
SCHEMBL14004015 0.88 RELA (0.45) NFE2L2RELAAPPTRPM8PTGS2
SCHEMBL6297043 0.87 NFE2L2 (0.39) NFE2L2RELAAPPTRPM8ALOX5
SCHEMBL6770761 0.87 NFE2L2 (0.39) NFE2L2RELAAPPTRPM8ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8349472-B2 Organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2013-01-08 US disclosed
US-8349472-B2 Organic electroluminescence device SAMSUNG DISPLAY CO., LTD. (KR) 2013-01-08 US disclosed
EP-1109235-B1 Organic electroluminescence device SAMSUNG SDI CO LTD (KR) 2008-08-20 EP disclosed