SCHEMBL14099797

SCHEMBL14099797

c1ccc(N(c2ccccc2)c2ccc3c(-c4ccc5c6cccc7cccc(c8cccc4c85)c76)c4cc(N(c5ccccc5)c5ccccc5)ccc4c(-c4ccc5c6cccc7cccc(c8cccc4c85)c76)c3c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.36
ERBB2 P04626 1/20 0.36
FYN P06241 1/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36
AHR P35869 1/20 0.36
ALDH1A1 P00352 3/20 0.34
HPGD P15428 2/20 0.34
HSD17B10 Q99714 2/20 0.34
THRB P10828 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15762797 0.95 ESR1 (0.33) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL14100086 0.94 CYP1A2 (0.32) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL12014686 0.90 CYP1A2 (0.40) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL14099800 0.88 HSD17B1 (0.32) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL12014688 0.86 CYP1A2 (0.37) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL15762792 0.85 CRHBP (0.39) CYP1A2ALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL8406123 0.85 SOS1 (0.39) CYP1A2ALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL12014672 0.85 SOS1 (0.39) CYP1A2ALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL14330789 0.85 CYP1A2 (0.36) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL14099827 0.84 ALDH1A1 (0.32) ALDH1A1HPGDHSD17B10CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9620721-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-11 US disclosed
US-9620721-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-11 US disclosed
US-8795855-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2014-08-05 US disclosed
US-8795855-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2014-08-05 US disclosed
US-20140151676-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2014-06-05 US disclosed
US-20140151676-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2014-06-05 US disclosed
US-20080182129-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC 2008-07-31 US disclosed
US-20080182129-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC 2008-07-31 US disclosed