Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14100010 | 0.82 | AGXT (0.37) | MAPTL3MBTL1GAAPOLBS1PR1 | |
| SCHEMBL14099947 | 0.81 | MAPT (0.33) | MAPTL3MBTL1GAAPOLBS1PR1 | |
| SCHEMBL14100095 | 0.81 | L3MBTL1 (0.46) | MAPTL3MBTL1GAAPOLBS1PR1 | |
| SCHEMBL14100045 | 0.80 | IDO1 (0.46) | MAPTL3MBTL1HTT | |
| SCHEMBL14099912 | 0.79 | MAPT (0.36) | MAPTL3MBTL1GAANPC1RAB9A | |
| SCHEMBL14099976 | 0.76 | NPC1 (0.49) | MAPTL3MBTL1CA12NPC1RAB9A | |
| SCHEMBL14100008 | 0.76 | MAPT (0.37) | MAPTNPC1SMN1; SMN2MAPK1HTT | |
| SCHEMBL10101733 | 0.76 | S1PR1 (0.60) | MAPTL3MBTL1GAAPOLBS1PR1 | |
| SCHEMBL14099908 | 0.76 | CCR2 (0.40) | MAPTL3MBTL1POLBSMN1; SMN2TDP1 | |
| SCHEMBL14099953 | 0.74 | S1PR1 (0.39) | MAPTL3MBTL1POLBS1PR1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799636-B1 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | SCHERING PLOUGH LTD (CH) | 2008-08-27 | — | — | EP | disclosed |