Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGXT | P21549 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14099956 | 0.85 | ALDH1A1 (0.35) | MAPTNPC1RAB9AMAPK1HTT | |
| SCHEMBL14099925 | 0.83 | CCR5 (0.41) | AGXTMAPTL3MBTL1NPC1RAB9A | |
| SCHEMBL14099896 | 0.82 | MAPT (0.46) | AGXTMAPTGAAL3MBTL1POLB | |
| SCHEMBL22326643 | 0.73 | AGXT (0.44) | AGXTMAPTGAAL3MBTL1POLB | |
| SCHEMBL14099953 | 0.71 | S1PR1 (0.39) | AGXTMAPTL3MBTL1POLBS1PR1 | |
| SCHEMBL14099950 | 0.70 | NPC1 (0.49) | MAPTL3MBTL1POLBNPC1RAB9A | |
| SCHEMBL14100095 | 0.69 | L3MBTL1 (0.46) | AGXTMAPTGAAL3MBTL1POLB | |
| SCHEMBL2755830 | 0.67 | L3MBTL1 (0.50) | AGXTMAPTGAAL3MBTL1POLB | |
| SCHEMBL14099947 | 0.67 | MAPT (0.33) | MAPTGAAL3MBTL1POLBS1PR1 | |
| SCHEMBL14099979 | 0.66 | MAPT (0.35) | MAPTGAANPC1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799636-B1 | CONTROL OF PARASITES IN ANIMALS BY THE USE OF NOVEL TRIFLUOROMETHANESULFONANILIDE OXIME ETHER DERIVATIVES | SCHERING PLOUGH LTD (CH) | 2008-08-27 | — | — | EP | disclosed |