Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.33 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL86073 | 0.99 | HSD11B1 (0.43) | HSD11B1POLBNPC1RAB9AHPGD | |
| SCHEMBL13564215 | 0.81 | HSD11B1 (0.39) | HSD11B1POLBNPC1RAB9AHPGD | |
| SCHEMBL2380585 | 0.80 | CYP3A4 (0.36) | ALDH1A1MAPTMAPK1EPHX1MEN1 | |
| SCHEMBL1105065 | 0.79 | HSD11B1 (0.40) | HSD11B1POLBNPC1RAB9AHPGD | |
| SCHEMBL14428637 | 0.78 | — | — | |
| SCHEMBL15935801 | 0.77 | — | — | |
| SCHEMBL13943429 | 0.76 | — | — | |
| SCHEMBL14370456 | 0.75 | HSD11B1 (0.43) | HSD11B1POLBNPC1RAB9AHPGD | |
| SCHEMBL2380586 | 0.75 | PEPD (0.34) | HPGDALDH1A1MAPTHSD17B10 | |
| SCHEMBL5412685 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1182188-B1 | Method for producing carboxylic acid tertiary alkyl ester | HONSHU CHEMICAL IND (JP) | 2011-03-09 | — | — | EP | disclosed |
| US-6492542-B2 | CONTINUALLY ADDING AN ESTERIFICATION AGENT POSSESSING A MONOVALENT ACID GROUP, WHICH AGENT IS ESTER-INTERCHANGEABLE WITH A TERTIARY ALCOHOL, TO A MIXED FLUID OF A CARBOXYLIC ACID AND A TERTIARY ALCOHOL | HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1182188-A2 | Method for producing carboxylic acid tertiary alkyl ester | Honshu Chemical Industry Co., Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |