Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9925442 | 0.80 | ALDH1A1 (0.49) | ALDH1A1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL14516867 | 0.80 | SMN1; SMN2 (0.40) | ALDH1A1TP53CYP3A4 | |
| SCHEMBL10005671 | 0.80 | ALDH1A1 (0.36) | ALDH1A1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL18132390 | 0.79 | ALDH1A1 (0.34) | ALDH1A1TP53CYP3A4 | |
| SCHEMBL12891600 | 0.79 | ALDH1A1 (0.34) | ALDH1A1TP53CYP3A4 | |
| SCHEMBL2850663 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL18879808 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL25797198 | 0.75 | ALDH1A1 (0.44) | ALDH1A1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL15339791 | 0.74 | MGLL (0.41) | ALDH1A1 | |
| SCHEMBL14520520 | 0.74 | ALDH1A1 (0.38) | ALDH1A1TP53CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399795-B2 | Surface modification of contact lenses | BAUSCH & LOMB INCORPORATED (US) | 2008-07-15 | — | — | US | disclosed |
| US-7270678-B2 | For reducing or eliminating lens epithelial cell growth thereon, reducing or eliminating silicone oil absorption upon subsequent surgical exposure and/ or reducing implantation inserter friction | BAUSCH & LOMB INCORPORATED (US) | 2007-09-18 | — | — | US | disclosed |