Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25797198 | 0.85 | ALDH1A1 (0.44) | ALDH1A1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL9925442 | 0.85 | ALDH1A1 (0.49) | ALDH1A1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL9952240 | 0.82 | ALDH1A1 (0.41) | ALDH1A1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL2203833 | 0.82 | TSHR (0.39) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL10773349 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL18879808 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL15868639 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL12900126 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TP53CYP3A4TSHRMAPK1 | |
| SCHEMBL23907058 | 0.78 | MMP8 (0.45) | ALDH1A1CYP3A4TSHR | |
| SCHEMBL30396753 | 0.78 | MMP8 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12503435-B2 | Aziridine functional compound | COVESTRO (NETHERLANDS) B.V. (NL) | 2025-12-23 | — | — | US | claimed |
| US-20230140764-A1 | AZIRIDINE FUNCTIONAL COMPOUND | COVESTRO (NETHERLANDS) B.V. (NL) | 2023-05-04 | — | — | US | claimed |
| EP-4093799-A1 | AZIRIDINE FUNCTIONAL COMPOUND | Covestro (Netherlands) B.V. (NL) | 2022-11-30 | — | — | EP | claimed |
| CN-115003722-A | Aziridine functional compounds | 科思创(荷兰)有限公司 | 2022-09-02 | — | — | CN | claimed |
| WO-2021148561-A1 | AZIRIDINE FUNCTIONAL COMPOUND | COVESTRO (NETHERLANDS) B.V. (NL) | 2021-07-29 | — | — | WO | claimed |
| US-12637423-B2 | Aziridinyl functional compound | COVESTRO (NETHERLANDS) B.V. (NL) | 2026-05-26 | — | — | US | disclosed |
| US-12565473-B2 | Coating composition | COVESTRO (NETHERLANDS) B.V. (NL) | 2026-03-03 | — | — | US | disclosed |
| WO-2026041607-A1 | AZIRIDINYL-FUNCTIONAL ORGANIC COMPOUNDS | COVESTRO (NETHERLANDS) B.V. (NL) | 2026-02-26 | — | — | WO | disclosed |
| US-12503435-B2 | Aziridine functional compound | COVESTRO (NETHERLANDS) B.V. (NL) | 2025-12-23 | — | — | US | disclosed |
| US-12398098-B2 | Waterborne crosslinker composition | COVESTRO (NETHERLANDS) B.V. (NL) | 2025-08-26 | — | — | US | disclosed |
| US-12378189-B2 | Multi-aziridine compound | COVESTRO (NETHERLANDS) B.V. (NL) | 2025-08-05 | — | — | US | disclosed |
| US-12378188-B2 | Waterborne crosslinker composition | COVESTRO (NETHERLANDS) B.V. (NL) | 2025-08-05 | — | — | US | disclosed |
| WO-2013072481-A1 | GLYCEROL DIESTERS, METHOD FOR PRODUCING SAME, AND USE OF SAME IN COATING AGENTS | BASF COATINGS GMBH (DE) | 2013-05-23 | — | — | WO | disclosed |
| US-20120157620-A1 | AMINE-EPOXY ADDUCTS AND THEIR USE FOR PREPARING POLYUREA AND POLYUREA-POLYURETHANE COATINGS | POLINVENT KFT. (HU) | 2012-06-21 | — | — | US | disclosed |
| US-20100126664-A1 | Polyester Polyols for Polyurethane Adhesives | STEPAN COMPANY | 2010-05-27 | — | — | US | disclosed |
| US-20060205909-A1 | Polyester polyols for polyurethane adhesives | O'BRIEN MICHAEL E | 2006-09-14 | — | — | US | disclosed |
| US-20050171301-A1 | Reworkable thermosetting resin compositions | LOCTITE CORPORATION | 2005-08-04 | — | — | US | disclosed |
| WO-2004083274-A1 | POLYESTER POLYOLS FOR POLYURETHANE ADHESIVES | STEPAN COMPANY (US) | 2004-09-30 | — | — | WO | disclosed |
| US-6656530-B2 | Automotive refinish coatings with low volatile organic content | BASF CORPORATION | 2003-12-02 | — | — | US | disclosed |
| US-20030149192-A1 | Automotive refinish coatings with low volatile organic content | BASF CORPORATION | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12565473-B2 | Coating composition | MSR1, MCHR1, SIGMAR1 | ALDH1A1 2723/4885TP53 3794/4885CYP3A4 1066/4885 |
| US-12398098-B2 | Waterborne crosslinker composition | AAAS, WDR48, WDR1 | ALDH1A1 202/4885TP53 1388/4885CYP3A4 1032/4885 |
| US-12378188-B2 | Waterborne crosslinker composition | HRH1, HRH2, CHRM1 | ALDH1A1 1522/4885TP53 2911/4885CYP3A4 1255/4885 |
| US-20120157620-A1 | AMINE-EPOXY ADDUCTS AND THEIR USE FOR PREPARING POLYUREA AND POLYUREA-POLYURETHANE COATINGS | PCNA, PNMT, CHKB | ALDH1A1 837/4885TP53 2772/4885CYP3A4 1812/4885 |
| US-12637423-B2 | Aziridinyl functional compound | FPR1, UTS2R, UQCRB | ALDH1A1 1232/4885TP53 4200/4885CYP3A4 995/4885 |
| US-12503435-B2 | Aziridine functional compound | AZI2, PCNA, OGG1 | ALDH1A1 1077/4885TP53 25/4885CYP3A4 1114/4885 |
| US-20230140764-A1 | AZIRIDINE FUNCTIONAL COMPOUND | AZI2, PCNA, OGG1 | ALDH1A1 1077/4885TP53 25/4885CYP3A4 1114/4885 |
| US-12378189-B2 | Multi-aziridine compound | QDPR, PRMT9, JMJD6 | ALDH1A1 494/4885TP53 2775/4885CYP3A4 3179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.