Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | GLA | P06280 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | KDM1A | O60341 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 3/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455804 | 0.88 | KDM4E (1.00) | MAPTKDM4EGLAKMT2AKDM1A | |
| SCHEMBL30003990 | 0.81 | KDM4E (0.70) | MAPTKDM4EGLAKMT2AKDM1A | |
| SCHEMBL4898172 | 0.81 | KDM4E (0.70) | MAPTKDM4EGLAKMT2AKDM1A | |
| SCHEMBL1502392 | 0.78 | ALDH1A1 (0.62) | MAPTKDM4EGLAKMT2AKDM1A | |
| SCHEMBL14100900 | 0.78 | KDM4E (0.55) | MAPTKDM4EGLAKMT2AKDM1A | |
| SCHEMBL14100961 | 0.77 | KDM4E (0.56) | MAPTKDM4EGLAKMT2AKDM1A | |
| SCHEMBL17423220 | 0.77 | KDM4E (0.78) | MAPTKDM4EGLAKMT2AKDM1A | |
| SCHEMBL14100955 | 0.77 | MAPT (0.55) | MAPTKDM4EGLAKMT2AKDM1A | |
| SCHEMBL14100949 | 0.76 | MAPT (0.54) | MAPTKDM4EGLAKMT2AKDM1A | |
| SCHEMBL13400206 | 0.76 | ALDH1A1 (0.59) | MAPTKDM4EGLAKMT2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080166593-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| US-20080166593-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080166593-A1 | Organic Electroluminescent Devices | OR10J3, DDT, EML4 | MAPT 882/4885KDM4E 1218/4885GLA 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.