Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | GLA | P06280 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | KDM1A | O60341 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 3/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17423220 | 0.88 | KDM4E (0.78) | KDM4EMAPTGLAKMT2AKDM1A | |
| SCHEMBL14100950 | 0.88 | MAPT (0.78) | KDM4EMAPTGLAKMT2AKDM1A | |
| SCHEMBL30863325 | 0.86 | KMT2A (0.75) | KDM4EMAPTGLAKMT2AKDM1A | |
| SCHEMBL6593133 | 0.84 | KDM1A (0.76) | KDM4EMAPTGLAKMT2AKDM1A | |
| SCHEMBL4898172 | 0.83 | KDM4E (0.70) | KDM4EMAPTGLAKMT2AKDM1A | |
| SCHEMBL30003990 | 0.83 | KDM4E (0.70) | KDM4EMAPTGLAKMT2AKDM1A | |
| SCHEMBL18631832 | 0.82 | MAPT (0.68) | KDM4EMAPTGLAKMT2AKDM1A | |
| SCHEMBL18650760 | 0.80 | MAPT (0.66) | KDM4EMAPTGLAKMT2AKDM1A | |
| SCHEMBL28627795 | 0.77 | KDM4E (0.63) | KDM4EMAPTGLAKMT2AKDM1A | |
| SCHEMBL1408391 | 0.74 | POLB (1.00) | KDM4EMAPTGLAKMT2AKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961801-B | A kind of synthesis and application of antibacterial polypeptide conjugate and its dimer with Mutiple Targets | 兰州大学 | 2018-01-19 | — | — | CN | claimed |
| CN-104961801-A | Antibacterial polypeptide conjugate with multiple target points and synthesis method and application of biopolymer of antibacterial polypeptide conjugate | UNIV LANZHOU | 2015-10-07 | — | — | CN | claimed |
| US-20250059224-A1 | PLATINUM-ACRIDINE COMPOUNDS AND METHODS OF TREATING CANCERS | WAKE FOREST UNIVERSITY (US) | 2025-02-20 | — | — | US | disclosed |
| US-12023341-B2 | Platinum-acridine compounds and methods of treating cancers | WAKE FOREST UNIVERSITY (US) | 2024-07-02 | — | — | US | disclosed |
| US-20210330679-A1 | PLATINUM-ACRIDINE COMPOUNDS AND METHODS OF TREATING CANCERS | WAKE FOREST UNIVERSITY (US) | 2021-10-28 | — | — | US | disclosed |
| US-20210330679-A1 | PLATINUM-ACRIDINE COMPOUNDS AND METHODS OF TREATING CANCERS | WAKE FOREST UNIVERSITY (US) | 2021-10-28 | — | — | US | disclosed |
| CN-107721925-B | Novel acetylcholinesterase inhibitor and preparation method and application thereof | 上海交通大学 | 2020-02-14 | — | — | CN | disclosed |
| US-10202349-B2 | Asymmetric bis-acridines with antitumour activity and their uses | Gdansk University of Technology (PL) | 2019-02-12 | — | — | US | disclosed |
| US-20180086712-A1 | ASYMMETRIC BIS-ACRIDINES WITH ANTITUMOUR ACTIVITY AND THEIR USES | Gdansk University of Technology (PL) | 2018-03-29 | — | — | US | disclosed |
| CN-104961801-B | A kind of synthesis and application of antibacterial polypeptide conjugate and its dimer with Mutiple Targets | 兰州大学 | 2018-01-19 | — | — | CN | disclosed |
| EP-3070078-B1 | ASYMMETRIC BIS-ACRIDINES WITH ANTITUMOR ACTIVITY AND USE THEREOF | POLITECHNIKA GDANSKA (PL) | 2017-10-04 | — | — | EP | disclosed |
| WO-1993019768-A1 | SELF-ASSEMBLING POLYNUCLEOTIDE DELIVERY SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1993-10-14 | — | — | WO | disclosed |
| EP-0172427-B1 | PROCESS FOR PRODUCTION OF VINYL CHLORIDE POLYMER | Shin-Etsu Chemical Co., Ltd. (JP) | 1989-07-05 | — | — | EP | disclosed |
| US-4758639-A | Process for production of vinyl polymer | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-19 | — | — | US | disclosed |
| US-4757124-A | Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0172427-A2 | Process for production of vinyl chloride polymer | Shin-Etsu Chemical Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
| EP-0039224-B1 | COMPOUND HAVING ANTITUMOUR PROPERTIES | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1984-06-27 | — | — | EP | disclosed |
| EP-0025705-B1 | COMPOUNDS HAVING ANTITUMOUR PROPERTIES, PROCESS FOR THEIR PREPARATION, THESE COMPOUNDS FOR USE AS ANTITUMOUR AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1983-06-22 | — | — | EP | disclosed |
| EP-0039224-A2 | Compound having antitumour properties | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1981-11-04 | — | — | EP | disclosed |
| EP-0025705-A1 | Compounds having antitumour properties, process for their preparation, these compounds for use as antitumour agents and pharmaceutical compositions containing them | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1981-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210330679-A1 | PLATINUM-ACRIDINE COMPOUNDS AND METHODS OF TREATING CANCERS | SLC47A1, SLC16A1, ABCC1 | KDM4E 2231/4885MAPT 3706/4885GLA 4715/4885 |
| US-10202349-B2 | Asymmetric bis-acridines with antitumour activity and their uses | MCL1, BAD, ACR | KDM4E 4576/4885MAPT 3943/4885GLA 3297/4885 |
| US-20250059224-A1 | PLATINUM-ACRIDINE COMPOUNDS AND METHODS OF TREATING CANCERS | SLC47A1, SLC16A1, ABCC1 | KDM4E 2231/4885MAPT 3706/4885GLA 4715/4885 |
| US-12023341-B2 | Platinum-acridine compounds and methods of treating cancers | SLC47A1, SLC16A1, ABCC1 | KDM4E 2231/4885MAPT 3706/4885GLA 4715/4885 |
| US-20180086712-A1 | ASYMMETRIC BIS-ACRIDINES WITH ANTITUMOUR ACTIVITY AND THEIR USES | MCL1, ACR, BAD | KDM4E 4561/4885MAPT 3707/4885GLA 3484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.