Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101031 | 0.85 | ALDH1A1 (0.38) | CYP1A2ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL14101020 | 0.81 | GAA (0.34) | CYP1A2ALDH1A1GAARCE1MCL1 | |
| SCHEMBL5746859 | 0.81 | CYP1A2 (0.50) | CYP1A2ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL14101004 | 0.77 | PPARG (0.42) | CYP1A2ALDH1A1HPGDGAARCE1 | |
| SCHEMBL14101009 | 0.77 | PPARG (0.40) | CYP1A2ALDH1A1GAARCE1CYP2C9 | |
| SCHEMBL443820 | 0.76 | GAA (0.61) | CYP1A2ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL30731587 | 0.76 | GAA (0.61) | CYP1A2ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL14101019 | 0.75 | MCL1 (0.36) | ALDH1A1GAACYP2C9CYP2C19MCL1 | |
| SCHEMBL28440233 | 0.74 | GAA (0.55) | CYP1A2ALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL13829351 | 0.73 | ESR1 (0.47) | HPGDGAARCE1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080166593-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| US-20080166593-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080166593-A1 | Organic Electroluminescent Devices | OR10J3, DDT, EML4 | CYP1A2 870/4885ALDH1A1 610/4885HPGD 2780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.