Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1179573 | 0.83 | IDO1 (0.55) | PNMTTAAR1SIGMAR1IDO1MEN1 | |
| SCHEMBL4742633 | 0.81 | PNMT (0.50) | PNMTTAAR1SIGMAR1IDO1IGF1R | |
| SCHEMBL177296 | 0.80 | PNMT (0.61) | PNMTTAAR1SIGMAR1IDO1IGF1R | |
| SCHEMBL30019331 | 0.80 | PNMT (0.61) | PNMTTAAR1SIGMAR1IDO1IGF1R | |
| SCHEMBL9613957 | 0.79 | TAAR1 (0.45) | TAAR1SIGMAR1IDO1IGF1RALOX15 | |
| SCHEMBL79213 | 0.76 | IGF1R (0.58) | PNMTTAAR1SIGMAR1IDO1IGF1R | |
| SCHEMBL3589323 | 0.76 | FFAR1 (0.51) | PNMTTAAR1SIGMAR1IGF1RALOX15 | |
| SCHEMBL16771200 | 0.75 | PNMT (0.55) | PNMTTAAR1SIGMAR1IDO1IGF1R | |
| SCHEMBL4741469 | 0.74 | FFAR1 (0.49) | PNMTTAAR1SIGMAR1IDO1IGF1R | |
| SCHEMBL7009306 | 0.73 | IGF1R (0.59) | PNMTTAAR1SIGMAR1IDO1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |