Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508195 | 1.00 | PGR (0.44) | PGRHTR2CGAASMN1; SMN2NOTUM | |
| SCHEMBL6652087 | 0.82 | OPRM1 (0.46) | GAASMN1; SMN2HTR2A | |
| SCHEMBL18293095 | 0.79 | NTRK1 (0.40) | HTR2CGAASMN1; SMN2NOTUMTP53 | |
| SCHEMBL30659732 | 0.77 | NTRK1 (0.39) | HTR2CGAASMN1; SMN2NOTUMHTR2A | |
| SCHEMBL29139839 | 0.77 | NTRK1 (0.39) | HTR2CGAASMN1; SMN2NOTUMHTR2A | |
| SCHEMBL5755544 | 0.77 | OPRM1 (0.43) | GAASMN1; SMN2 | |
| SCHEMBL30659759 | 0.77 | NTRK1 (0.39) | HTR2CGAASMN1; SMN2NOTUMHTR2A | |
| SCHEMBL15717177 | 0.77 | NTRK1 (0.39) | HTR2CGAASMN1; SMN2NOTUMHTR2A | |
| SCHEMBL15717022 | 0.77 | NTRK1 (0.39) | HTR2CGAASMN1; SMN2NOTUMHTR2A | |
| SCHEMBL5447481 | 0.77 | NTRK1 (0.39) | HTR2CGAASMN1; SMN2NOTUMHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953154-A1 | MORPHOLINE TYPE CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2008-08-06 | — | — | EP | disclosed |