Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652087 | 0.91 | OPRM1 (0.46) | OPRM1OPRD1OPRK1OPRL1GAA | |
| SCHEMBL14101425 | 0.77 | PGR (0.44) | GAASMN1; SMN2 | |
| SCHEMBL1508195 | 0.77 | PGR (0.44) | GAASMN1; SMN2 | |
| SCHEMBL18192162 | 0.75 | HTR2A (0.43) | OPRM1GAASMN1; SMN2PRCP | |
| SCHEMBL5748613 | 0.73 | PDE7A (0.33) | TRPA1 | |
| SCHEMBL10603757 | 0.72 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1GAA | |
| SCHEMBL30337114 | 0.70 | OPRM1 (0.45) | OPRM1OPRD1OPRK1OPRL1GAA | |
| SCHEMBL10192534 | 0.70 | OPRM1 (0.45) | OPRM1OPRD1OPRK1OPRL1GAA | |
| SCHEMBL16543135 | 0.70 | OPRM1 (0.45) | OPRM1OPRD1OPRK1OPRL1GAA | |
| SCHEMBL24969376 | 0.70 | PDK2 (0.41) | OPRL1GAASMN1; SMN2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6982348-B2 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-01-03 | — | — | US | disclosed |
| US-20040127574-A1 | Aminoethanol derivatives | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-07-01 | — | — | US | disclosed |
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127574-A1 | Aminoethanol derivatives | CETP, LCAT, MTTP | OPRM1 2976/4885OPRD1 1598/4885OPRK1 2041/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.