Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17552740 | 0.79 | RIPK1 (0.40) | MEN1KMT2ARIPK1CES2CES1 | |
| SCHEMBL20332825 | 0.76 | RIPK1 (0.38) | MEN1KMT2ACNR1CNR2RIPK1 | |
| SCHEMBL3947336 | 0.72 | MEN1 (0.41) | MEN1KMT2ARIPK1CES2CES1 | |
| SCHEMBL7847209 | 0.72 | GABRA1 (0.43) | MEN1KMT2ARIPK1CES2CES1 | |
| SCHEMBL27223742 | 0.72 | PRKAB2 (0.40) | CNR1CNR2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL15678401 | 0.71 | CNR2 (0.56) | MEN1KMT2ACNR1CNR2 | |
| SCHEMBL15506136 | 0.71 | GABRA1 (0.50) | MEN1KMT2ACNR1CNR2 | |
| SCHEMBL14101539 | 0.71 | MEN1 (0.35) | MEN1KMT2A | |
| SCHEMBL186541 | 0.70 | CNR1 (0.42) | MEN1KMT2ACNR1CNR2PRKAB2 | |
| SCHEMBL22980343 | 0.70 | ESR1 (0.52) | MEN1KMT2ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953154-A1 | MORPHOLINE TYPE CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2008-08-06 | — | — | EP | disclosed |