SCHEMBL14101558

SCHEMBL14101558

CC1(C)c2ccccc2-c2ccc(-c3ccc4sc5ccc(-c6ccc7ccccc7c6)cc5c4c3)cc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 1/20 0.36
LIPG Q9Y5X9 1/20 0.36
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
PDK2 Q15119 4/20 0.34
S1PR5 Q9H228 6/20 0.34
S1PR4 O95977 4/20 0.34
GSTP1 P09211 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
CYP1A2 P05177 2/20 0.33
ALOX5 P09917 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PTGER3 P43115 1/20 0.33
AR P10275 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP2C9 P11712 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10018885 0.92 PDK2 (0.38) PDK2
SCHEMBL13488031 0.90 S1PR5 (0.32) LPLLIPGSLC6A2SLC6A4SLC6A3
SCHEMBL14101648 0.90 LPL (0.36) LPLLIPGSLC6A2SLC6A4SLC6A3
SCHEMBL18086207 0.88 GPR3 (0.40) PDK2CYP1A2ALOX5SMN1; SMN2ALDH1A1
SCHEMBL20698555 0.88 ALOX5 (0.41) SLC6A2SLC6A4SLC6A3PDK2S1PR5
SCHEMBL27864761 0.87 LPL (0.44) LPLLIPGSLC6A2SLC6A4SLC6A3
SCHEMBL14101564 0.86 PDK2 (0.35) PDK2
SCHEMBL23179314 0.86 S1PR5 (0.32) LPLLIPGSLC6A2SLC6A4SLC6A3
SCHEMBL23179742 0.86 S1PR5 (0.32) LPLLIPGSLC6A2SLC6A4SLC6A3
SCHEMBL14101557 0.86 ALOX5 (0.38) PDK2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080166594-A1 BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-07-10 US disclosed
US-20080166594-A1 BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080166594-A1 BENZOTHIOPHENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE MAKING USE OF THE SAME CYBA, BPNT1, TYR LPL 3027/4885LIPG 2557/4885SLC6A2 719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.