Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723472 | 0.88 | P2RX7 (0.39) | NOTUMALDH1A1PARP1MEN1KMT2A | |
| SCHEMBL4723471 | 0.88 | P2RX7 (0.39) | NOTUMALDH1A1PARP1MEN1KMT2A | |
| SCHEMBL4720254 | 0.86 | PARP1 (0.39) | MAPK1ALDH1A1KDM4EL3MBTL1PARP1 | |
| SCHEMBL14101736 | 0.83 | NOTUM (0.37) | NOTUMMAPK1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL14101711 | 0.83 | MAPT (0.42) | NOTUMMAPK1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL14101882 | 0.82 | KDM4E (0.39) | NOTUMMAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL14101794 | 0.82 | PTGS2 (0.42) | NOTUMMAPK1ALDH1A1KDM4EMAPT | |
| SCHEMBL14101783 | 0.82 | NOTUM (0.38) | NOTUMMAPK1ALDH1A1MAPTHTT | |
| SCHEMBL14101706 | 0.82 | MAPT (0.38) | NOTUMMAPK1ALDH1A1L3MBTL1MAPT | |
| SCHEMBL14101895 | 0.81 | P2RX7 (0.38) | NOTUMMAPK1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |