Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 9/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891051 | 0.85 | CCR3 (0.55) | CCR3ACHEBCHE | |
| SCHEMBL8245441 | 0.84 | ACHE (0.67) | CCR3ACHEALDH1A1CXCR4 | |
| SCHEMBL20257208 | 0.84 | CCR3 (0.53) | CCR3ACHEBCHEALDH1A1CXCR4 | |
| SCHEMBL15140944 | 0.83 | CCR3 (0.73) | CCR3ACHEBCHEALDH1A1CXCR4 | |
| SCHEMBL69200 | 0.82 | CCR3 (0.67) | CCR3ACHEBCHEALDH1A1CXCR4 | |
| SCHEMBL9163513 | 0.82 | CCR3 (0.48) | CCR3ACHEBCHE | |
| SCHEMBL3107807 | 0.82 | CCR3 (0.71) | CCR3ACHEBCHEALDH1A1CXCR4 | |
| SCHEMBL5234223 | 0.81 | ACHE (0.56) | CCR3ACHECXCR4 | |
| SCHEMBL22751978 | 0.81 | ACHE (0.58) | CCR3ACHEBCHEALDH1A1CXCR4 | |
| SCHEMBL17562354 | 0.81 | ACHE (0.58) | CCR3ACHEBCHEALDH1A1CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234936-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | LEADINGTAC PHARMACEUTICAL (SHAOXING) CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
| US-20230234936-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | LEADINGTAC PHARMACEUTICAL (SHAOXING) CO., LTD. (CN) | 2023-07-27 | — | — | US | disclosed |
| US-9546153-B2 | Bicyclic heterocycle substituted pyridyl compounds useful as kinase modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-01-17 | — | — | US | disclosed |
| US-20150274696-A1 | BICYCLIC HETEROCYCLE SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2015-10-01 | — | — | US | disclosed |
| WO-2008094208-A2 | PROTEIN KINASE TARGETED THERAPEUTICS | NORTHWESTERN UNIVERSITY (US) | 2008-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234936-A1 | COMPOUND FOR TARGETING AND DEGRADING PROTEIN, AND PREPARATION METHOD THEREFOR AND USE THEREOF | IRAK4, IRAK2, IRAK1 | CCR3 1597/4885ACHE 3442/4885BCHE 2328/4885 |
| US-20150274696-A1 | BICYCLIC HETEROCYCLE SUBSTITUTED PYRIDYL COMPOUNDS USEFUL AS KINASE MODULATORS | IRAK4, IRAK1, IRAK3 | CCR3 1411/4885ACHE 4610/4885BCHE 4682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.