SCHEMBL3107807

SCHEMBL3107807

c1ccc(CN2CCC(CCCC3CCN(Cc4ccccc4)CC3)CC2)cc1

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 1/20 0.71
ACHE P22303 8/20 0.63
BCHE P06276 2/20 0.63
ALDH1A1 P00352 1/20 0.61
CXCR4 P61073 1/20 0.61
SIGMAR1 Q99720 2/20 0.61
DRD2 P14416 1/20 0.60
HTR2A P28223 1/20 0.60
HTR2C P28335 1/20 0.60
HTR2B P41595 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4499239 0.95 CCR3 (0.69) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL4499901 0.95 CCR3 (0.69) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL6847071 0.91 CCR3 (0.70) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL17262668 0.91 DRD2 (0.68) CCR3ACHEBCHESIGMAR1DRD2
SCHEMBL15140944 0.91 CCR3 (0.73) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL8883264 0.90 CCR3 (0.63) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL8908408 0.90 CCR3 (0.63) CCR3ACHEBCHE
SCHEMBL7371344 0.90 SIGMAR1 (0.67) CCR3ACHEBCHESIGMAR1DRD2
SCHEMBL3457881 0.90 CCR3 (0.63) CCR3ACHEBCHEALDH1A1CXCR4
SCHEMBL6846812 0.90 CCR3 (0.68) CCR3ACHEBCHEALDH1A1CXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4018071-A None JP disclosed
EP-2236461-B1 Method for synthesizing all-silica zeolite beta with small crystal size FORMOSAN UNION CHEMICAL CORP (TW) 2015-10-14 EP disclosed
US-8206683-B2 Method for synthesizing all-silica zeolite beta with small crystal size FORMOSAN UNION CHEMICAL CORP. (TW) 2012-06-26 US disclosed
US-20100254894-A1 METHOD FOR SYNTHESIZING ALL-SILICA ZEOLITE BETA WITH SMALL CRYSTAL SIZE FORMOSAN UNION CHEMICAL CORP. (TW) 2010-10-07 US disclosed
EP-2236461-A1 Method for synthesizing all-silica zeolite beta with small crystal size Formosan Union Chemical Corp. (TW) 2010-10-06 EP disclosed
US-5554356-A Method of making essentially silicic zeolite beta ARCO CHEMICAL TECHNOLOGY, L.P. (US) 1996-09-10 US disclosed
JP-H0418071-A BISPIPERIDINE DERIVATIVE SUMITOMO PHARMACEUT CO LTD 1992-01-22 JP disclosed