Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102447 | 0.82 | CCR3 (0.61) | CCR3ACHEBCHE | |
| SCHEMBL3891051 | 0.75 | CCR3 (0.55) | CCR3ACHEBCHE | |
| SCHEMBL8245441 | 0.73 | ACHE (0.67) | CCR3ACHE | |
| SCHEMBL15140944 | 0.73 | CCR3 (0.73) | CCR3ACHEBCHE | |
| SCHEMBL5234228 | 0.73 | CCR3 (0.52) | CCR3ACHESLC6A3BCHEDRD2 | |
| SCHEMBL69200 | 0.72 | CCR3 (0.67) | CCR3ACHEBCHE | |
| SCHEMBL3107807 | 0.71 | CCR3 (0.71) | CCR3ACHEBCHEDRD2 | |
| SCHEMBL5234223 | 0.71 | ACHE (0.56) | CCR3ACHESLC6A3 | |
| SCHEMBL585809 | 0.71 | ACHE (0.50) | CCR3ACHEBCHE | |
| SCHEMBL27862871 | 0.71 | ACHE (0.50) | CCR3ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650474-A1 | NOVEL PIPERIDYL AMIDES, SULFONAMIDES AND SULFOXAMIDES AS INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | MERRELL PHARMACEUTICALS INC. (US) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994001404-A1 | NOVEL PIPERIDYL AMIDES, SULFONAMIDES AND SULFOXAMIDES AS INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1994-01-20 | — | — | WO | disclosed |