Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 6/20 | 0.38 |
| ▸ | CDK1 | P06493 | 6/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 6/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 6/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | AHCY | P23526 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20052009 | 0.80 | CCNB2 (0.44) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL20052010 | 0.79 | CCNB2 (0.40) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL20052944 | 0.78 | AHCY (0.43) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL14102249 | 0.78 | CCNB2 (0.38) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL13443481 | 0.77 | TDP1 (0.41) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL17552180 | 0.77 | AHCY (0.39) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL13443484 | 0.76 | L3MBTL1 (0.41) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL13896532 | 0.76 | AHCY (0.40) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL18521958 | 0.76 | CCNB2 (0.42) | CCNB2CDK1CCNB1CCNB3CDK2 | |
| SCHEMBL13896531 | 0.76 | CCNB2 (0.37) | CCNB2CDK1CCNB1CCNB3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008100447-A2 | NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2008-08-21 | — | — | WO | disclosed |