SCHEMBL28299700

SCHEMBL28299700

C=c1c2ccccc2c(=C)c2c(Cl)cccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.46
CYP1A2 P05177 4/20 0.46
TSHR P16473 3/20 0.39
LMNA P02545 1/20 0.39
NR4A2 P43354 1/20 0.37
TYMS P04818 1/20 0.34
DYRK1A Q13627 2/20 0.34
ALDH1A1 P00352 3/20 0.33
IDO1 P14902 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33
GABRA1 P14867 1/20 0.33
GABRB1 P18505 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
GABRB2 P47870 1/20 0.33
GABRA4 P48169 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14023491 0.81 CYP2A6 (0.41) CYP2A6CYP1A2NR4A2TYMSALDH1A1
SCHEMBL26144812 0.74 ALDH1A1 (0.32) CYP1A2ALDH1A1HPGD
SCHEMBL2522240 0.74 ALDH1A1 (0.41) CYP2A6CYP1A2TSHRALDH1A1IDO1
SCHEMBL10431739 0.72 CYP1A2 (0.58) CYP2A6CYP1A2TSHRLMNANR4A2
SCHEMBL14375343 0.72 CYP1A2 (0.65) CYP2A6CYP1A2TSHRLMNANR4A2
SCHEMBL32666063 0.69 CYP2A6 (0.52) CYP2A6CYP1A2TSHRLMNANR4A2
SCHEMBL528105 0.69 CYP2A6 (0.52) CYP2A6CYP1A2TSHRLMNANR4A2
SCHEMBL20783732 0.68 MAPT (0.48) CYP1A2TSHRLMNADYRK1AALDH1A1
SCHEMBL14103296 0.68 IDO1 (0.38) TSHRALDH1A1IDO1POLBMAPT
SCHEMBL13121562 0.67 CYP2A6 (0.58) CYP2A6CYP1A2TSHRLMNANR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109721721-B Polyether with fluorescence property and synthetic method and application thereof 万华化学集团股份有限公司 2021-05-14 CN claimed
CN-109721721-A A kind of polyethers and its synthetic method and application with photoluminescent property 万华化学集团股份有限公司 2019-05-07 CN claimed
CN-109721721-B Polyether with fluorescence property and synthetic method and application thereof 万华化学集团股份有限公司 2021-05-14 CN disclosed
CN-109721721-A A kind of polyethers and its synthetic method and application with photoluminescent property 万华化学集团股份有限公司 2019-05-07 CN disclosed