Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.37 |
| ▸ | MTOR | P42345 | 3/20 | 0.37 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.37 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | PRKACG | P22612 | 1/20 | 0.37 |
| ▸ | PRKACB | P22694 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14104151 | 0.87 | PIK3CA (0.39) | CSNK2A1PIK3CAMTORPIK3C2BCCNE2 | |
| SCHEMBL14104413 | 0.87 | CSNK2A1 (0.42) | CSNK2A1TSPOABL1NPC1RAB9A | |
| SCHEMBL14103742 | 0.83 | RAB9A (0.43) | PIK3CAMTORPIK3C2BCCNE2PRKACA | |
| SCHEMBL14103741 | 0.80 | MAPT (0.49) | PIK3CAMTORPIK3C2BCCNE2PRKACA | |
| SCHEMBL14104415 | 0.78 | PIK3CA (0.46) | CSNK2A1PIK3CAMTORPIK3C2BCCNE2 | |
| SCHEMBL14104146 | 0.77 | AXL (0.40) | CSNK2A1PIK3CAMTORPIK3C2BCCNE2 | |
| SCHEMBL14104075 | 0.77 | CYP1A2 (0.40) | CSNK2A1TSPOKDRABCG2MAPT | |
| SCHEMBL14095203 | 0.77 | PRKCI (0.39) | PIK3CAMTORPIK3C2BCCNE2PRKACA | |
| SCHEMBL13789439 | 0.76 | AXL (0.39) | CSNK2A1ABL1PIK3CAMTORPIK3C2B | |
| SCHEMBL14095156 | 0.75 | CASP3 (0.45) | PIK3CAMTORPIK3C2BCCNE2PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008092861-A1 | BICYCLIC DERIVATIVES AS EP4 AGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-08-07 | — | — | WO | disclosed |