SCHEMBL14106913

SCHEMBL14106913

CN1C(=O)c2ccc(Oc3ccc(Oc4ccc5c(c4)C(=O)N(C)C5=O)cc3)cc2C1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.56
MEN1 O00255 3/20 0.56
KMT2A Q03164 3/20 0.56
KDM4E B2RXH2 2/20 0.56
POLB P06746 2/20 0.56
HTT P42858 1/20 0.56
HSD17B10 Q99714 3/20 0.54
APP P05067 3/20 0.54
MAPK1 P28482 2/20 0.54
LPAR1 Q92633 1/20 0.54
LPAR3 Q9UBY5 1/20 0.54
TDP1 Q9NUW8 1/20 0.53
MAOA P21397 2/20 0.49
MAOB P27338 2/20 0.49
MAPT P10636 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
ALOX15 P16050 1/20 0.49
APAF1 O14727 1/20 0.48
BRD4 O60885 1/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL262253 0.98 ALDH1A1 (0.57) ALDH1A1MEN1KMT2AKDM4EPOLB
SCHEMBL18117700 0.94 ALDH1A1 (0.51) ALDH1A1MEN1KMT2AKDM4EPOLB
SCHEMBL8737302 0.94 LPAR1 (0.61) ALDH1A1MEN1KMT2AKDM4EPOLB
SCHEMBL11095064 0.93 MAOA (0.60) ALDH1A1MEN1KMT2AKDM4EPOLB
SCHEMBL617579 0.91 ALDH1A1 (0.51) ALDH1A1MEN1KMT2AKDM4EPOLB
SCHEMBL12799185 0.91 LPAR1 (0.58) ALDH1A1MEN1KMT2AKDM4EPOLB
SCHEMBL14439307 0.90 BRD4 (0.62) ALDH1A1MEN1KMT2AKDM4EPOLB
SCHEMBL23240780 0.88 ALDH1A1 (0.50) ALDH1A1MEN1KMT2AKDM4EPOLB
SCHEMBL13899281 0.88 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AKDM4EPOLB
SCHEMBL84288 0.88 ALDH1A1 (0.47) ALDH1A1MEN1KMT2AKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7404312-B2 Humidity-sensitive element for humidity sensor NIPPON SOKEN, INC. (JP) 2008-07-29 US disclosed