Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | APP | P05067 | 2/20 | 0.53 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.52 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14106913 | 0.93 | ALDH1A1 (0.56) | MAOAMAOBAPPLPAR1LPAR3 | |
| SCHEMBL262253 | 0.91 | ALDH1A1 (0.57) | APPLPAR1LPAR3TDP1KDM4E | |
| SCHEMBL18117700 | 0.88 | ALDH1A1 (0.51) | MAOAMAOBAPPLPAR1LPAR3 | |
| SCHEMBL8737302 | 0.88 | LPAR1 (0.61) | MAOAMAOBAPPLPAR1LPAR3 | |
| SCHEMBL12799185 | 0.85 | LPAR1 (0.58) | MAOAMAOBAPPLPAR1LPAR3 | |
| SCHEMBL617579 | 0.85 | ALDH1A1 (0.51) | APPLPAR1LPAR3TDP1KDM4E | |
| SCHEMBL14439307 | 0.83 | BRD4 (0.62) | LPAR1LPAR3TDP1KDM4EALDH1A1 | |
| SCHEMBL10000952 | 0.83 | BRD4 (0.55) | MAOAMAOBLPAR1LPAR3ALDH1A1 | |
| SCHEMBL14010053 | 0.82 | BRD4 (0.58) | APPLPAR1LPAR3TDP1ALDH1A1 | |
| SCHEMBL23240780 | 0.82 | ALDH1A1 (0.50) | MAOAMAOBAPPLPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3573615-B1 | A PROCESS FOR PREPARING 5-PHENOXY-1(3H)ISOBENZOFURANONE | KINGCHEM LIFE SCIENCE LLC (US) | 2024-06-12 | — | — | EP | disclosed |
| CN-110225753-B | Process for preparing 5-phenoxy-1 (3H) isobenzofuranones | 金凯(辽宁)生命科技股份有限公司 | 2022-12-09 | — | — | CN | disclosed |
| US-10611745-B2 | Process for preparing 5-phenoxy-1(3)isobenzofuranone | KINGCHEM LIFE SCIENCE LLC (US) | 2020-04-07 | — | — | US | disclosed |
| US-20190225591-A1 | PROCESS FOR PREPARING 5-PHENOXY-1(3)ISOBENZOFURANONE | KINGCHEM LIFE SCIENCE LLC | 2019-07-25 | — | — | US | disclosed |
| US-20190225591-A1 | PROCESS FOR PREPARING 5-PHENOXY-1(3)ISOBENZOFURANONE | KINGCHEM LIFE SCIENCE LLC | 2019-07-25 | — | — | US | disclosed |
| WO-2018140186-A1 | A PROCESS FOR PREPARING 5-PHENOXY-1(3H)ISOBENZOFURANONE | KINGCHEM LIFE SCIENCE LLC (US) | 2018-08-02 | — | — | WO | disclosed |
| WO-2018140186-A1 | A PROCESS FOR PREPARING 5-PHENOXY-1(3H)ISOBENZOFURANONE | KINGCHEM LIFE SCIENCE LLC (US) | 2018-08-02 | — | — | WO | disclosed |
| US-4471125-A | Method for making aromatic ether imides | GENERAL ELECTRIC COMPANY (US) | 1984-09-11 | — | — | US | disclosed |
| US-4217281-A | Imide carbonyl compounds and method for making | GENERAL ELECTRIC COMPANY (US) | 1980-08-12 | — | — | US | disclosed |
| US-4128574-A | FROM AN IMIDE | GENERAL ELECTRIC COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225591-A1 | PROCESS FOR PREPARING 5-PHENOXY-1(3)ISOBENZOFURANONE | PPOX, KCNA5, KCNH2 | MAOA 238/4885MAOB 110/4885APP 2407/4885 |
| US-10611745-B2 | Process for preparing 5-phenoxy-1(3)isobenzofuranone | PPOX, KCNA5, KCNH2 | MAOA 238/4885MAOB 110/4885APP 2407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.