Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 17/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5103907 | 0.69 | HTR6 (0.77) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL14106926 | 0.69 | ALDH1A1 (0.37) | KDM4EALDH1A1LMNAHTR6 | |
| SCHEMBL14107093 | 0.69 | HTR6 (0.46) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL14107050 | 0.66 | HTR6 (0.56) | HTR6HTR1ADRD2HTR3EHTR3B | |
| SCHEMBL5095082 | 0.66 | HTR6 (0.60) | HTR6HTR1ADRD2HTR3EHTR3B | |
| SCHEMBL5091061 | 0.66 | HTR6 (0.64) | HTR6HTR1ADRD2HTR3EHTR3B | |
| SCHEMBL5095041 | 0.66 | HTR6 (0.52) | ALDH1A1LMNAHTR6HTR1ADRD2 | |
| SCHEMBL5091047 | 0.65 | HTR6 (0.63) | HTR6HTR1ADRD2HTR7 | |
| SCHEMBL14107044 | 0.65 | HTR6 (0.60) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL5103386 | 0.65 | HTR6 (0.54) | HTR6HTR1ADRD2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008101247-A2 | 6 ' SUBSTITUTED INDOLE AND INDAZOLE DERIVATIVES HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2008-08-21 | — | — | WO | disclosed |