Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 8/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14106930 | 0.71 | DYRK1A (0.37) | ALDH1A1KDM4ELMNAHTR6CHRNB2 | |
| SCHEMBL14107045 | 0.69 | HTR6 (0.50) | HTR6 | |
| SCHEMBL14106935 | 0.69 | KDM4E (0.40) | ALDH1A1KDM4ELMNAHTR6 | |
| SCHEMBL14106929 | 0.69 | GHSR (0.38) | ALDH1A1KDM4ELMNAHTR6 | |
| SCHEMBL14106941 | 0.69 | HTR6 (0.54) | HTR6MAPT | |
| SCHEMBL22673263 | 0.64 | ADRB1 (0.58) | HTR6CHRNB2CHRNA4CHRNA1CHRNA7 | |
| SCHEMBL27263501 | 0.62 | PIK3CD (0.61) | ALDH1A1KDM4ELMNAHTR6CHRNB2 | |
| SCHEMBL30826872 | 0.62 | PIK3CD (0.61) | ALDH1A1KDM4ELMNAHTR6CHRNB2 | |
| Hydrochloric Acid SCHEMBL3214277 | 0.60 | CHRNB2 (0.62) | ALDH1A1KDM4ELMNACHRNB2CHRNA4 | |
| SCHEMBL24028031 | 0.59 | CHRNB2 (0.58) | ALDH1A1KDM4ELMNACHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008101247-A2 | 6 ' SUBSTITUTED INDOLE AND INDAZOLE DERIVATIVES HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2008-08-21 | — | — | WO | disclosed |