Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | GLA | P06280 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13704047 | 0.81 | ALDH1A1 (0.71) | KDM4EKMT2AMEN1TSHRGAA | |
| SCHEMBL4742790 | 0.78 | KMT2A (0.54) | KDM4EKMT2AMEN1TSHRGAA | |
| SCHEMBL4740862 | 0.76 | ALDH1A1 (0.58) | KDM4EKMT2AMEN1TSHRGAA | |
| SCHEMBL13704156 | 0.75 | TSHR (0.64) | KDM4EKMT2AMEN1TSHRGAA | |
| SCHEMBL14583024 | 0.74 | KDM4E (0.66) | KDM4EKMT2AMEN1TSHRGAA | |
| SCHEMBL13704104 | 0.73 | KDM4E (0.59) | KDM4EKMT2AMEN1TSHRGAA | |
| SCHEMBL13704051 | 0.72 | POLB (0.67) | KDM4EKMT2AMEN1TSHRGAA | |
| SCHEMBL14583257 | 0.71 | KDM4E (0.68) | KDM4EKMT2AMEN1TSHRGAA | |
| SCHEMBL13704151 | 0.71 | KDM4E (0.68) | KDM4EKMT2AMEN1TSHRGAA | |
| SCHEMBL13704064 | 0.70 | ALDH1A1 (0.59) | KDM4EKMT2AMEN1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099021-A1 | DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-08-21 | — | — | WO | disclosed |