Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14106953 | 0.78 | KDM4E (0.60) | KMT2ATSHRMEN1GLAGAA | |
| SCHEMBL13704047 | 0.76 | ALDH1A1 (0.71) | KMT2ATSHRMEN1GLAGAA | |
| SCHEMBL4743201 | 0.75 | ALDH1A1 (0.50) | KMT2ATSHRMEN1GLAGAA | |
| SCHEMBL4740862 | 0.70 | ALDH1A1 (0.58) | KMT2ATSHRMEN1GLAGAA | |
| SCHEMBL13704104 | 0.70 | KDM4E (0.59) | KMT2ATSHRMEN1GLAGAA | |
| SCHEMBL4742336 | 0.69 | MEN1 (0.48) | KMT2ATSHRMEN1GLAGAA | |
| SCHEMBL14102180 | 0.68 | KMT2A (0.75) | KMT2ATSHRMEN1GLAGAA | |
| SCHEMBL13704064 | 0.68 | ALDH1A1 (0.59) | KMT2ATSHRMEN1GLAGAA | |
| SCHEMBL11747295 | 0.67 | KMT2A (0.71) | KMT2ATSHRMEN1GLAGAA | |
| SCHEMBL25791850 | 0.67 | ALDH1A1 (0.71) | KMT2ATSHRMEN1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099021-A1 | DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-08-21 | — | — | WO | disclosed |
| WO-2008099021-A1 | DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS | TIBOTEC PHARMACEUTICALS LTD. (IE) | 2008-08-21 | — | — | WO | disclosed |