Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 18/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14107936 | 0.91 | VDR (0.53) | VDR | |
| SCHEMBL14107927 | 0.84 | VDR (0.50) | VDRMEN1NR1I2PGRKMT2A | |
| SCHEMBL14107928 | 0.84 | VDR (0.54) | VDRMEN1NR1I2PGRKMT2A | |
| SCHEMBL14107948 | 0.78 | VDR (0.55) | VDRMEN1NR1I2PGRKMT2A | |
| SCHEMBL818214 | 0.78 | VDR (0.51) | VDR | |
| SCHEMBL817092 | 0.78 | VDR (0.51) | VDR | |
| SCHEMBL14107951 | 0.78 | VDR (0.52) | VDRMEN1NR1I2PGRKMT2A | |
| SCHEMBL14107943 | 0.77 | VDR (0.63) | VDRMEN1NR1I2PGRKMT2A | |
| SCHEMBL14107933 | 0.77 | VDR (0.46) | VDR | |
| SCHEMBL14107930 | 0.77 | VDR (0.52) | VDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402688-B2 | 2,2-Di-substituted 1alpha,25-dihydroxy-19-norvitamin D derivative | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-07-22 | — | — | US | disclosed |