SCHEMBL14112043

SCHEMBL14112043

CC1C(C)(C)c2ccc(CP(=O)(O)CC(CCC(N)=O)C(=O)O)cc2C1(C)C

nearest known ligand 0.50

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.37
GRM3 Q14832 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4873599 0.87 FOLH1 (0.34) FOLH1GRM3
SCHEMBL4874698 0.85 FOLH1 (0.39) FOLH1GRM3
SCHEMBL4874207 0.84 CYP26B1 (0.44) FOLH1
SCHEMBL14112042 0.76 FOLH1 (0.42) FOLH1GRM3
SCHEMBL4868657 0.75 FOLH1 (0.51) FOLH1GRM3
SCHEMBL6682065 0.73 MMP1 (0.46) FOLH1
SCHEMBL4873564 0.72 FOLH1 (0.45) FOLH1GRM3
SCHEMBL5051119 0.67 GRM3 (0.59) FOLH1GRM3
SCHEMBL5054385 0.66 FOLH1 (0.55) FOLH1GRM3
SCHEMBL5054661 0.66 GRM3 (0.54) FOLH1GRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7402576-B2 Phosphinic acid analogs of glutamate GIVAUDAN SA (CH) 2008-07-22 US disclosed
US-7402576-B2 Phosphinic acid analogs of glutamate GIVAUDAN SA (CH) 2008-07-22 US disclosed
EP-1599487-B1 PHOSPHINIC ACID ANALOGS OF GLUTAMATE GIVAUDAN SA (CH) 2007-07-11 EP disclosed