SCHEMBL6682065

SCHEMBL6682065

NC(=O)CCC(CP(=O)(O)Cc1cccc(-c2ccccc2)c1)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 2/20 0.46
FOLH1 Q04609 1/20 0.44
GGPS1 O95749 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14112042 0.83 FOLH1 (0.42) FOLH1
SCHEMBL4868961 0.80 MMP1 (0.45) MMP1FOLH1
SCHEMBL1373664 0.78 GRM3 (0.65) FOLH1
SCHEMBL4868657 0.78 FOLH1 (0.51) MMP1FOLH1
SCHEMBL4874778 0.77 LAP3 (0.47) FOLH1
SCHEMBL4874207 0.77 CYP26B1 (0.44) FOLH1
SCHEMBL5134279 0.76 MMP13 (0.60) MMP1
SCHEMBL4865803 0.76 TSHR (0.49) FOLH1
SCHEMBL5054385 0.76 FOLH1 (0.55) FOLH1
SCHEMBL7760292 0.76 FOLH1 (0.55) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7402576-B2 Phosphinic acid analogs of glutamate GIVAUDAN SA (CH) 2008-07-22 US disclosed
US-7402576-B2 Phosphinic acid analogs of glutamate GIVAUDAN SA (CH) 2008-07-22 US disclosed
EP-1599487-B1 PHOSPHINIC ACID ANALOGS OF GLUTAMATE GIVAUDAN SA (CH) 2007-07-11 EP disclosed
WO-2004048394-A1 PHOSPHINIC ACID ANALOGS OF GLUTAMATE GIVAUDAN SA (CH) 2004-06-10 WO disclosed