Sugi Predict

Sugi Predict / Compounds / SCHEMBL14113261

SCHEMBL14113261

SCHEMBL14113261

O=C1c2c(O)cccc2C(C2c3cccc(O)c3C(=O)c3c(O)cccc32)c2cccc(O)c21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 2/20 0.56
▸ ALDH1A1 P00352 2/20 0.56
▸ MAPT P10636 2/20 0.56
▸ ALOX15 P16050 2/20 0.56
▸ TSHR P16473 2/20 0.56
▸ HSD17B10 Q99714 2/20 0.56
▸ TDP1 Q9NUW8 2/20 0.56
▸ LMNA P02545 1/20 0.56
▸ HPGD P15428 1/20 0.56
▸ MAOB P27338 1/20 0.56
▸ MAPK1 P28482 1/20 0.56
▸ HTT P42858 1/20 0.56
▸ SMN1; SMN2 Q16637 1/20 0.56
▸ MEN1 O00255 1/20 0.52
▸ USP2 O75604 1/20 0.52
▸ HPN P05981 1/20 0.52
▸ CYP3A4 P08684 1/20 0.52
▸ ALOX5 P09917 1/20 0.52
▸ THRB P10828 1/20 0.52
▸ PTGS1 P23219 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10490934 0.84 ALDH1A1 (0.55) MAOAALDH1A1MAPTALOX15TSHR
SCHEMBL8559808 0.83 ALDH1A1 (0.52) MAOAALDH1A1MAPTALOX15TSHR
SCHEMBL10490982 0.82 ALDH1A1 (0.47) MAOAALDH1A1MAPTALOX15TSHR
Sennidin A SCHEMBL17166295 0.82 TDP1 (0.60) ALDH1A1MAPTALOX15TSHRHSD17B10
Sennidin A SCHEMBL30479184 0.82 TDP1 (0.60) ALDH1A1MAPTALOX15TSHRHSD17B10
Sennidin A SCHEMBL31373186 0.82 TDP1 (0.60) ALDH1A1MAPTALOX15TSHRHSD17B10
Sennidin A SCHEMBL30452211 0.82 TDP1 (0.60) ALDH1A1MAPTALOX15TSHRHSD17B10
Sennidin A SCHEMBL17166294 0.82 TDP1 (0.60) ALDH1A1MAPTALOX15TSHRHSD17B10
SCHEMBL10630399 0.78 ALDH1A1 (0.47) MAOAALDH1A1MAPTALOX15TSHR
SCHEMBL9421974 0.78 ALDH1A1 (0.47) MAOAALDH1A1MAPTALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080171795-A1 Dithranol, phospholipid, cholesterol, butylated hydroxytoluene as antioxidant, hydrocolloid gelling agent; and phosphate saline buffer; skin disorders such as psoriasis, chronic eczemas, dermatophytoses, alopecia areata, and seborrheic dermatitis LIFE-CARE INNOVATIONS PVT. LTD. (IN) 2008-07-17 — — US disclosed
US-20080171795-A1 Dithranol, phospholipid, cholesterol, butylated hydroxytoluene as antioxidant, hydrocolloid gelling agent; and phosphate saline buffer; skin disorders such as psoriasis, chronic eczemas, dermatophytoses, alopecia areata, and seborrheic dermatitis LIFE-CARE INNOVATIONS PVT. LTD. (IN) 2008-07-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080171795-A1 Dithranol, phospholipid, cholesterol, butylated hydroxytoluene as antioxidant, hydrocolloid gelling agent; and phosphate saline buffer; skin disorders such as psoriasis, chronic eczemas, dermatophytoses, alopecia areata, and seborrheic dermatitis CETP, LIPA, DHCR7 MAOA 1908/4885ALDH1A1 4414/4885MAPT 335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.