Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPN | P05981 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14113261 | 0.83 | MAOA (0.56) | ALDH1A1MAPTALOX15TSHRHSD17B10 | |
| SCHEMBL10490934 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MAPTALOX15TSHRHSD17B10 | |
| SCHEMBL10630399 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTALOX15TSHRHSD17B10 | |
| SCHEMBL10490982 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTALOX15TSHRHSD17B10 | |
| SCHEMBL9421974 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MAPTALOX15TSHRHSD17B10 | |
| SCHEMBL9628552 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPTALOX15TSHRHSD17B10 | |
| SCHEMBL10490976 | 0.72 | MEN1 (0.54) | ALDH1A1MAPTALOX15TSHRHSD17B10 | |
| SCHEMBL10631861 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTALOX15TSHRHSD17B10 | |
| Danthron SCHEMBL20565674 | 0.71 | MAPT (0.95) | ALDH1A1MAPTALOX15TSHRHSD17B10 | |
| SCHEMBL10490945 | 0.71 | ALDH1A1 (0.43) | ALDH1A1MAPTALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1496975-A | Emodin derivative with anti-tumour activity | 上海恒达科技发展股份有限公司 | 2004-05-19 | — | — | CN | disclosed |
| US-5705533-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1998-01-06 | — | — | US | disclosed |
| EP-0314405-B1 | NEW COMPOUNDS OF THE ANTHRAQUINONE SERIES | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 1992-03-18 | — | — | EP | disclosed |
| US-4997961-A | Compounds of the anthraquinone series | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 1991-03-05 | — | — | US | disclosed |
| EP-0386050-A1 | NEW COMPOUNDS OF THE ANTHRAQUINONE SERIES | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 1990-09-12 | — | — | EP | disclosed |
| US-4927845-A | Compounds of the anthraquinone series | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 1990-05-22 | — | — | US | disclosed |
| WO-1989003822-A1 | NEW COMPOUNDS OF THE ANTHRAQUINONE SERIES | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 1989-05-05 | — | — | WO | disclosed |
| EP-0314405-A1 | New compounds of the anthraquinone series | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 1989-05-03 | — | — | EP | disclosed |