Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | RECQL | P46063 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | CASP1 | P29466 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | CASP7 | P55210 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TTR | P02766 | 2/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sennidin A SCHEMBL17166295 | 1.00 | TDP1 (0.60) | TDP1MEN1CYP3A4MAPTHPGD | |
| Sennidin A SCHEMBL30479184 | 1.00 | TDP1 (0.60) | TDP1MEN1CYP3A4MAPTHPGD | |
| Sennidin A SCHEMBL30452211 | 1.00 | TDP1 (0.60) | TDP1MEN1CYP3A4MAPTHPGD | |
| Sennidin A SCHEMBL31373186 | 1.00 | TDP1 (0.60) | TDP1MEN1CYP3A4MAPTHPGD | |
| SCHEMBL17166019 | 0.93 | TDP1 (0.53) | TDP1MEN1CYP3A4MAPTHPGD | |
| SCHEMBL17166023 | 0.93 | TDP1 (0.53) | TDP1MEN1CYP3A4MAPTHPGD | |
| SCHEMBL31216666 | 0.92 | EPHX2 (0.55) | TDP1MEN1CYP3A4MAPTHPGD | |
| SCHEMBL31216679 | 0.84 | EPHX2 (0.48) | TDP1MEN1CYP3A4MAPTHPGD | |
| SCHEMBL14113261 | 0.82 | MAOA (0.56) | TDP1MEN1CYP3A4MAPTHPGD | |
| Rhein SCHEMBL29404324 | 0.75 | ALDH1A1 (1.00) | TDP1MEN1CYP3A4MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9155792-B2 | RecA inhibitors with antibiotic activity, compositions and methods of use | TRUSTEES OF BOSTON UNIVERSITY (US) | 2015-10-13 | — | — | US | disclosed |