Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 10/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CD38 | P28907 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3891828 | 0.87 | NPC1 (0.34) | KDM4EGRM4AKR1B1MAPTMAPK1 | |
| SCHEMBL1411642 | 0.84 | KDM4E (0.36) | KDM4EGRM4AKR1B1MAPTMITF | |
| SCHEMBL1411476 | 0.81 | AKR1B1 (0.44) | KDM4EGRM4AKR1B1MAPTMITF | |
| SCHEMBL1411742 | 0.76 | ALDH1A1 (0.44) | KDM4EAKR1B1MAPTLMNAHPGD | |
| SCHEMBL1411592 | 0.75 | PSEN1 (0.51) | GRM4MAPTHPGDHTTALDH1A1 | |
| SCHEMBL1411788 | 0.74 | KDM4E (0.32) | KDM4EAKR1B1SMN1; SMN2 | |
| SCHEMBL2203131 | 0.73 | — | — | |
| SCHEMBL4630244 | 0.70 | PSIP1 (0.32) | — | |
| SCHEMBL1410968 | 0.69 | HTT (0.41) | KDM4EMAPTLMNAHPGDMAPK1 | |
| SCHEMBL1028093 | 0.66 | GAA (0.32) | MAPTLMNAHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2294058-A1 | 2-(BENZYLSULFONYL)-OXAZOLE DERIVATIVES, CHIRAL 2- (BENZYLSULFINYL) -OXAZOLE DERIVATIVES AND 2-(BENZYLSULFANYL)-OXAZOLE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer CropScience AG (DE) | 2011-03-16 | — | — | EP | disclosed |
| WO-2009129953-A1 | 2-(BENZYLSULFONYL)-OXAZOLE DERIVATIVES, CHIRAL 2- (BENZYLSULFINYL) -OXAZOLE DERIVATIVES AND 2-(BENZYLSULFANYL)-OXAZOLE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2009-10-29 | — | — | WO | disclosed |
| EP-2112143-A1 | 2-(benzylsulfonyl)-oxazol-derivatives, chiral 2-(benzylsulfinyl]-oxazol derivatives, 2-(benzylsulfanyl-oxazol) derivatives, process for their preparation, as well as their use as herbicide and plant growth regulators | Bayer CropScience AG (DE) | 2009-10-28 | — | — | EP | disclosed |