Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1411552 | 0.84 | KDM4E (0.41) | KDM4EAKR1B1MITFLMNAMAPT | |
| SCHEMBL1411502 | 0.81 | GRM4 (0.30) | GRM4 | |
| SCHEMBL1411788 | 0.79 | KDM4E (0.32) | KDM4EAKR1B1 | |
| SCHEMBL1411476 | 0.78 | AKR1B1 (0.44) | KDM4EAKR1B1MITFLMNAMAPT | |
| SCHEMBL1411592 | 0.74 | PSEN1 (0.51) | MAPTHPGDHTTGRM4PSEN1 | |
| SCHEMBL3891828 | 0.73 | NPC1 (0.34) | KDM4EAKR1B1MAPTMAPK1NPSR1 | |
| SCHEMBL2203131 | 0.70 | — | — | |
| SCHEMBL270487 | 0.69 | PSEN1 (0.35) | KDM4EP2RX7AKR1B1PSEN1PSEN2 | |
| SCHEMBL1028374 | 0.68 | ALDH1A1 (0.41) | LMNAMAPTHTTNPSR1 | |
| SCHEMBL1411527 | 0.68 | NPC1 (0.37) | KDM4EP2RX7LMNAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110190125-A1 | 2-(BENZYLSULFONYL)OXAZOLE DERIVATIVES, CHIRAL 2-(BENZYLSULFINYL)OXAZOLE DERIVATIVES... | BAYER CROPSCIENCE AG (DE) | 2011-08-04 | — | — | US | disclosed |
| EP-2294058-A1 | 2-(BENZYLSULFONYL)-OXAZOLE DERIVATIVES, CHIRAL 2- (BENZYLSULFINYL) -OXAZOLE DERIVATIVES AND 2-(BENZYLSULFANYL)-OXAZOLE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | Bayer CropScience AG (DE) | 2011-03-16 | — | — | EP | disclosed |
| WO-2009129953-A1 | 2-(BENZYLSULFONYL)-OXAZOLE DERIVATIVES, CHIRAL 2- (BENZYLSULFINYL) -OXAZOLE DERIVATIVES AND 2-(BENZYLSULFANYL)-OXAZOLE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2009-10-29 | — | — | WO | disclosed |
| EP-2112143-A1 | 2-(benzylsulfonyl)-oxazol-derivatives, chiral 2-(benzylsulfinyl]-oxazol derivatives, 2-(benzylsulfanyl-oxazol) derivatives, process for their preparation, as well as their use as herbicide and plant growth regulators | Bayer CropScience AG (DE) | 2009-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190125-A1 | 2-(BENZYLSULFONYL)OXAZOLE DERIVATIVES, CHIRAL 2-(BENZYLSULFINYL)OXAZOLE DERIVATIVES... | BBOX1, STS, OXA1L | KDM4E 1358/4885P2RX7 2308/4885AKR1B1 469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.