Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.42 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322824 | 0.89 | MAPT (0.42) | RECQLTSHRSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL2431695 | 0.86 | HPGD (0.60) | TSHRSMN1; SMN2ALDH1A1HPGDLMNA | |
| SCHEMBL2226272 | 0.85 | TSHR (0.56) | RECQLTSHRSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3810198 | 0.85 | TSHR (0.56) | RECQLTSHRSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL21140576 | 0.85 | TSHR (0.56) | RECQLTSHRSMN1; SMN2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL27080322 | 0.84 | HPGD (0.58) | TSHRSMN1; SMN2ALDH1A1HPGDLMNA | |
| SCHEMBL415383 | 0.83 | SMN1; SMN2 (0.50) | RECQLTSHRSMN1; SMN2ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL1226221 | 0.83 | TSHR (0.54) | RECQLTSHRSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL13097124 | 0.82 | RECQL (0.49) | RECQLTSHRSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL18433296 | 0.82 | ALDH1A1 (0.68) | TSHRSMN1; SMN2ALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12486222-B2 | Compounds as soluble epoxide hydrolase inhibitors | UNIVERSITAT DE BARCELONA (ES) | 2025-12-02 | — | — | US | disclosed |
| US-20250115548-A1 | COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | UNIV BARCELONA (ES) | 2025-04-10 | — | — | US | disclosed |
| US-20240400575-A1 | POLYCYCLIC COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | UNIV BARCELONA (ES) | 2024-12-05 | — | — | US | disclosed |
| US-20240182406-A1 | COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | UNIVERSITAT DE BARCELONA (ES) | 2024-06-06 | — | — | US | disclosed |
| CN-118019728-A | Compounds as soluble epoxide hydrolase inhibitors | 巴塞罗那大学 | 2024-05-10 | — | — | CN | disclosed |
| EP-4313947-A1 | COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | Universitat de Barcelona (ES) | 2024-02-07 | — | — | EP | disclosed |
| EP-3810572-B1 | POLYCYCLIC COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | UNIV BARCELONA (ES) | 2023-11-15 | — | — | EP | disclosed |
| CN-112888674-B | Polycyclic compounds as soluble epoxide hydrolase inhibitors | 巴塞罗那大学 | 2023-06-30 | — | — | CN | disclosed |
| WO-2022200105-A1 | COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | UNIVERSITAT DE BARCELONA (ES) | 2022-09-29 | — | — | WO | disclosed |
| EP-4063348-A1 | COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | Universitat de Barcelona (ES) | 2022-09-28 | — | — | EP | disclosed |
| US-20080175914-A1 | Pyrazolo[3,4-b]Pyridine Compounds, and their Use as Phosphodiesterase Inhibitors | GLAXO GROUP LIMITED | 2008-07-24 | — | — | US | disclosed |
| US-20080175914-A1 | Pyrazolo[3,4-b]Pyridine Compounds, and their Use as Phosphodiesterase Inhibitors | GLAXO GROUP LIMITED | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182406-A1 | COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | EPHX1, EPHX2, LTA4H | RECQL 1060/4885TSHR 3701/4885SMN1; SMN2 4582/4885 |
| US-20250115548-A1 | COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | EPHX1, EPHX2, LTA4H | RECQL 1060/4885TSHR 3701/4885SMN1; SMN2 4582/4885 |
| US-20080175914-A1 | Pyrazolo[3,4-b]Pyridine Compounds, and their Use as Phosphodiesterase Inhibitors | PDE5A, PDE3B, PDE4A | RECQL 925/4885TSHR 1794/4885SMN1; SMN2 4454/4885 |
| US-12486222-B2 | Compounds as soluble epoxide hydrolase inhibitors | EPHX1, EPHX2, LTA4H | RECQL 1060/4885TSHR 3701/4885SMN1; SMN2 4582/4885 |
| US-20240400575-A1 | POLYCYCLIC COMPOUNDS AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | EPHX1, EPHX2, NCEH1 | RECQL 1119/4885TSHR 4075/4885SMN1; SMN2 4747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.