Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 10/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.54 |
| ▸ | STK10 | O94804 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12424836 | 0.91 | PTGS2 (0.62) | GSK3BPTGS2STK10CLK2GSK3A | |
| SCHEMBL91966 | 0.86 | PTGS2 (0.50) | GSK3BPTGS2GSK3ARECQLALDH1A1 | |
| SCHEMBL13222334 | 0.85 | PTGS2 (0.56) | GSK3BPTGS2STK10CLK2GSK3A | |
| SCHEMBL12509755 | 0.83 | PTGS2 (0.54) | GSK3BPTGS2STK10CLK2GSK3A | |
| SCHEMBL7753950 | 0.81 | CYP2D6 (0.46) | GSK3BPTGS2GSK3ARECQLRAB9A | |
| SCHEMBL13222110 | 0.81 | PTGS2 (0.64) | GSK3BPTGS2STK10CLK2GSK3A | |
| SCHEMBL13143797 | 0.79 | PTGS2 (0.42) | GSK3BPTGS2GSK3ARECQLMAPK1 | |
| SCHEMBL1557806 | 0.79 | GSK3B (0.54) | GSK3BPTGS2MEN1CYP1A2KMT2A | |
| SCHEMBL14614520 | 0.77 | IDO1 (0.48) | GSK3BPTGS2GSK3ARECQLALDH1A1 | |
| SCHEMBL21419776 | 0.77 | GSK3B (0.58) | GSK3BPTGS2STK10GSK3ASLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417154-B2 | Heat-stable diketopyrrolopyrrole pigment mixtures | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-08-26 | — | — | US | disclosed |