SCHEMBL91966

SCHEMBL91966

O=C1NC(c2ccc(Cl)cc2)=C2C(=O)NC(c3ccc(Cl)cc3)=C12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.50
GSK3B P49841 11/20 0.47
RECQL P46063 1/20 0.43
GSK3A P49840 1/20 0.42
ALDH1A1 P00352 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
TSHR P16473 1/20 0.41
TDP2 O95551 1/20 0.41
PPOX P50336 1/20 0.39
NOTUM Q6P988 1/20 0.38
JAK2 O60674 1/20 0.38
NTRK1 P04629 1/20 0.38
MET P08581 1/20 0.38
FGFR1 P11362 1/20 0.38
PRKACA P17612 1/20 0.38
KDR P35968 1/20 0.38
MAP2K2 P36507 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1557806 0.92 GSK3B (0.54) PTGS2GSK3BKDM4EGAAMAPT
SCHEMBL12577463 0.90 PTGS2 (0.44) PTGS2GSK3BRECQLGSK3AALDH1A1
SCHEMBL92072 0.90 CYP1A2 (0.56) PTGS2GSK3BKDM4EGAAMAPT
SCHEMBL12640594 0.90 PTGS2 (0.44) PTGS2GSK3BRECQLGSK3AALDH1A1
SCHEMBL7753950 0.90 CYP2D6 (0.46) PTGS2GSK3BRECQLGSK3AALDH1A1
SCHEMBL14614520 0.90 IDO1 (0.48) PTGS2GSK3BRECQLGSK3AALDH1A1
SCHEMBL21419776 0.90 GSK3B (0.58) PTGS2GSK3BRECQLGSK3AMAPT
SCHEMBL13143797 0.89 PTGS2 (0.42) PTGS2GSK3BRECQLGSK3AALDH1A1
SCHEMBL7750652 0.87 AHR (0.43) PTGS2GSK3BGSK3AALDH1A1KDM4E
SCHEMBL14115809 0.86 GSK3B (0.61) PTGS2GSK3BRECQLGSK3AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 676 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577368-B2 Opaque polyester-based materials HOLLAND COLOURS N.V. (NL) 2026-03-17 US claimed
EP-4592335-A1 PIGMENT CONCENTRATES Lifocolor Farben GmbH & Co. KG (DE) 2025-07-30 EP claimed
EP-4520796-A1 STERILIZATION RESISTANT AQUEOUS PRINTING PRIMER PRINTABLE WITH RADIATION CURABLE LACQUERS AND DEEP DRAWABLE Constantia Teich GmbH (AT) 2025-03-12 EP claimed
US-20250075051-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2025-03-06 US claimed
EP-4457275-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2024-11-06 EP claimed
CN-117425369-A Light-emitting element and manufacturing method thereof 台州观宇科技有限公司 2024-01-19 CN claimed
WO-2023126441-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2023-07-06 WO claimed
EP-4206267-A1 PROCESS FOR RECYCLING CONTAMINATED POLYMERS ARKEMA FRANCE (FR) 2023-07-05 EP claimed
CN-115595681-A Fibers having physical properties for encoding 伊士曼化工公司(US) 2023-01-13 CN claimed
US-20220282060-A1 OPAQUE POLYESTER-BASED MATERIALS HOLLAND COLOURS N.V. (NL) 2022-09-08 US claimed
US-6036766-A SPINNING SOLUTIONS, PAINTS, COATINGS, PRINTING INKS CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-03-14 US claimed
EP-0794235-B1 Ternary solid solutions of 1,4-diketo-pyrrolopyrroles and quinacridones CIBA SC HOLDING AG (CH) 2000-02-02 EP claimed
EP-0704496-B1 Pigmentary solid solutions of pyrrolo 3,4-C pyrroles and quinacridones CIBA SC HOLDING AG (CH) 1999-11-24 EP claimed
US-5565578-A PURIFYING THE CHROME RED BY SALT FORMATION WITH A BASE DISSOLVING IN DIMETHYLSULFOXIDE, DESALTING IN ALKANOL CIBA-GEIGY CORPORATION (US) 1996-10-15 US claimed
EP-0466646-B1 Process for distortion-free pigmentation of polyolefins CIBA GEIGY AG (CH) 1996-08-28 EP claimed
EP-0719842-A2 Pigment compositions for coatings CIBA-GEIGY AG (CH) 1996-07-03 EP claimed
US-5529623-A Pigmentary solid solutions of pyrrolo[3,4-c]pyrroles and quinacridones CIBA-GEIGY CORPORATION (US) 1996-06-25 US claimed
EP-0704496-A1 Pigmentary solid solutions of pyrrolo 3,4-C pyrroles and quinacridones CIBA-GEIGY AG (CH) 1996-04-03 EP claimed
US-5274010-A Process for warp-free pigmenting of polyolefins CIBA-GEIGY CORPORATION (US) 1993-12-28 US claimed
EP-0466646-A1 Process for distortion-free pigmentation of polyolefins CIBA-GEIGY AG (CH) 1992-01-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577368-B2 Opaque polyester-based materials STRA6, RICTOR, RPL35 PTGS2 610/4885GSK3B 3008/4885RECQL 2232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.