Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 11/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91966 | 0.90 | PTGS2 (0.50) | PTGS2GSK3BGSK3ARECQLTDP2 | |
| SCHEMBL12509900 | 0.90 | PTGS2 (0.32) | IDO1PTGS2 | |
| SCHEMBL13222114 | 0.84 | GSK3B (0.43) | GSK3BGSK3ATDP2 | |
| SCHEMBL1557806 | 0.83 | GSK3B (0.54) | PTGS2GSK3BKDM4EGAAMAPT | |
| SCHEMBL92072 | 0.81 | CYP1A2 (0.56) | PTGS2GSK3BTDP2KDM4EGAA | |
| SCHEMBL21419776 | 0.81 | GSK3B (0.58) | PTGS2GSK3BGSK3ARECQLMAPT | |
| SCHEMBL12577463 | 0.81 | PTGS2 (0.44) | PTGS2GSK3BGSK3ARECQLTDP2 | |
| SCHEMBL7753950 | 0.81 | CYP2D6 (0.46) | PTGS2GSK3BGSK3ARECQLALDH1A1 | |
| SCHEMBL12640594 | 0.81 | PTGS2 (0.44) | PTGS2GSK3BGSK3ARECQLTDP2 | |
| SCHEMBL14614527 | 0.81 | PTGS2 (0.44) | PTGS2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070028807-A1 | Heat-stable diketopyrrolopyrrole pigment mixtures | CIBA SPECIALTY CHEMICALS CORP. | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070028807-A1 | Heat-stable diketopyrrolopyrrole pigment mixtures | NDUFS5, CBR3, CYB5R3 | IDO1 2271/4885PTGS2 3448/4885GSK3B 3986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.